Dietary inulin intake and age can significantly affect intestinal absorption of calcium and magnesium in rats: a stable isotope approach

Table 3 Effect of age and inulin intake and their interaction on intestinal absorption and retention of Ca in rats

	Cont 3 Mo	Cont 6 Mo	Cont 11 Mo	Cont 21 Mo	Inulin 3 Mo	Inulin 6 Mo	Inulin 11 Mo	Inulin 21 Mo	inulin	age	interaction
Administered ⁴⁴ Ca, μg	1637 ± 46	1610 ± 14	1602 ± 17	1605 ± 24	1593 ± 19	1614 ± 19	1621 ± 25	1626 ± 22	NS	NS	<0.0005
Fecal ⁴⁴ Ca enrichment, %	12.5 ± 3.3	17.3 ± 2.4	20.2 ± 4.3	18.7 ± 2.8	10.9 ± 4.2	17.8 ± 6.2	17.4 ± 2.1	21.2 ± 3.1	NS	<0.0001	NS
Fecal ⁴⁴ Ca level, μg/g	112 ± 30	182 ± 35	218 ± 45	204 ± 38	76 ± 30	152 ± 49	163 ± 26	188 ± 26	<0.0001	<0.0001	NS
Fecal ⁴⁴ Ca excretion, μg	856 ± 224	1139 ± 153	1389 ± 96	1366 ± 115	541 ± 223	926 ± 142	1207 ± 195	1192 ± 142	<0.0001	<0.0001	NS
Intestinal ⁴⁴ Ca absorption, μg	781 ± 206	471 ± 153	213 ± 90	239 ± 117	1052 ± 222	689 ± 142	413 ± 202	434 ± 143	<0.0001	<0.0001	NS
Intestinal ⁴⁴ Ca absorption, %	47.8 ± 12.9	29.3 ± 9.4	13.3 ± 5.6	14.9 ± 7.3	66.1 ± 13.9	42.7 ± 8.8	25.4 ± 12.4	26.7 ± 8.7	<0.0001	<0.0001	NS
Urinary ⁴⁴ Ca enrichment, %	17.4 ± 6.5	20.6 ± 6.7	14.8 ± 3.1	16.9 ± 3.9	13.7 ± 3.3	17.5 ± 6.7	18.6 ± 4.2	18.5 ± 4.1	NS	NS	0.0569
Urinary ⁴⁴ Ca excretion, μg	15.3 ± 5.9	14.8 ± 6.0	25.8 ± 10.7	28.1 ± 7.9	23.5 ± 7.2	21.8 ± 9.9	49.0 ± 11.8	40.3 ± 12.5	<0.0001	<0.0001	0.036
⁴⁴ Ca retention, μg	765 ± 204	456 ± 153	188 ± 92	212 ± 113	1029 ± 219	667 ± 135	364 ± 203	394 ± 145	<0.0001	<0.0001	NS
⁴⁴ Ca retention, %	46.9 ± 12.8	28.3 ± 9.5	11.7 ± 5.7	13.2 ± 7.1	64.6 ± 13.8	41.3 ± 8.3	22.4 ± 12.4	24.2 ± 8.9	<0.0001	<0.0001	NS

Values are mean ± SD, n = 10 animals.
The rats were given ⁴⁴Ca after 14 days of inulin intake (7.5%), and fecal non-absorbed ⁴⁴Ca isotope was determined in a 4d feces and urine pools.

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