Figure 10

Representative immunohistochemistry patterns of p53, annexin IV and VEGF in animal tumor sections. p53 expression was stained as positive (+) in SKOV3 only and SKOV3 plus H₂O groups, treatment of 4-HPR was slightly changes its expression and most of nuclei were stained negative (upper panel). Cactus extract treatment was found in some of nuclei stained negative (weak). Annexin IV expression was detected negatively (-) in SKOV3 only and SKOV3 plus H₂O groups, treatment of both 4-HPR and cactus extracts were increased its expression (mid panel). VEGF expression was detected positively (+) in SKOV3 only and SKOV3 plus H₂O groups, treatment of both 4-HPR and cactus extracts were decreased its expression (bottom panel).