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Table 2 Statistical analysis of Study 2 scores of wellbeing (Winter 2002–2003).

From: Randomized comparison of the effects of the vitamin D3adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients

  Intent-to-treat analysis Per-protocol analysis
Dose of Vitamin D N Age   N  
mcg/day (IU/day) Total in group, (% female) yr (SD) 25(OH)D nmol/L (SD) December
2002 Score
(out of 16)
February
2003
Score
(out of 16)
Total in group,
(% female)
December
2002 Score
(out of 16)
February
2003 Score
(out of 16)
CONTINUERS FROM STUDY 1 (on Vit D since previous year)
15 (600) 22 (77%) 54 (14) 69 (26) 7.2 (4.5) 4.4 (3.4) 15 (73%) 6.9 (4.8) 4.4 (3.4) b
100 (4000) 24 (84%) 56 (9) 126 (45) a 4.4 (4.4) a 4.0 (3.7) 16 (88%) 4.6 (4.6) 4.0 (3.7)
NEW PATIENTS FOR STUDY 2
15 (600) 33 (68%) 48 (13) 39 (9) 8.0 (5.2) 5.4 (4.3) 25 (64%) 8.7 (5.5) 5.4 (4.3) b
100 (4000) 33 (85%) 50 (14) 39 (9) 8.4 (5.5) 3.9 (3.6) c 26 (89%) 8.1 (5.6) 3.9 (3.6) bc
  1. a Different from 15 mcg (600 IU)/day group (the value above the mean marked by this footnote) by t-test p < 0.04; lower (better) than in the 600 IU/day group by Mann-Whitney p = 0.039.
  2. b Paired t-test, December score vs February Score (the value to the left of the mean marked by this footnote) p < 0.012; also significant by the non-parametric equivalent to paired t-test, the Wilcoxan test, p < 0.012.
  3. c For New patients, low vs high dose group, 2-tail unpaired t test p = 0.188; Mann-Whitney p = 0.183; i.e. not significantly different.
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