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Table 1 Statistical analysis of Study 1 scores of wellbeing (Winter 2001–2002).

From: Randomized comparison of the effects of the vitamin D3adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients

  Intent-to-treat analysis Per-protocol analysis
Dose of Vitamin D N Age    N   
mcg/day (IU/day) Total in group, (% female)   December 2001
Score out of 6;
mean (SD)
February 2002
Score out of 6;
mean (SD)
Total in group,
(% female)
December 2001
Score out of 6;
mean (SD)
February 2002
Score out of 6;
mean (SD)
15 (600) 32 (80%) 53 (14) 2.2 (2.0) 2.3 (2.3) 16 (80%) 2.4 (2.2) 2.3 (2.4)
100 (4000) 32 (83%) 55 (9) 2.0 (2.3) 1.1 (1.8) a 21 (83%) 1.5 (2.2) 1.0 (1.5) bc
  1. a February scores for 100 mcg (4000 IU)/day were lower (better) than in the 15 mcg (600 IU)/day group by two-tail t-score p = 0.072; Mann-Whitney p = 0.072; these 2-tail values are equivalent to 1-tail significance.
  2. b Paired t-test, December score vs February Score p = 0.097; or non-parametric Sign test, p = 0.109.
  3. c Difference between dose groups by t-test p = 0.047; by Mann-Whitney test p = 0.072 (this 2-tail value is equivalent to 1-tail significance)
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