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Table 1 Geometric mean hormone levels (ng/dL) for participants on 0 g alcohol and % change (Δ) in hormone levels from 0 g to 15 g and 30 g alcohol per day at weeks 4 and 8

From: The effects of moderate alcohol supplementation on estrone sulfate and DHEAS in postmenopausal women in a controlled feeding study

Hormone   0 g/d, mean (95% C.I.) 15 g/d, Δ (95% C.I.)* 30 g/d, Δ (95% C.I.)* P-trend†
Estrone Sulfate (4 wk) 47.5 (39.2–57.4) 6.9% (-4.2%–19.3%) 22.2% (9.4%–36.5%) 0.0006
  (8 wk) 47.4 (40.5–55.6) 7.5% (-0.3%–15.9%) 10.7% (2.7%–19.3%) 0.009
DHEAS (4 wk) 55.3 (47.0–65.1) 8.0% (4.5%–11.6%) 9.2% (5.6%–12.8%) <0.0001
  (8 wk) 59.4 (50.5–70.0) 5.1% (1.4%–9.0%) 7.5% (3.7%–11.5%) 0.0001
  1. * Estimates of percent change are from linear mixed models, including participant as a random effect and alcohol levels as fixed effects treated as two indicator variables.
  2. P-trend values (two-sided) are from linear mixed models, including participant as a random effect and alcohol levels as a continuous fixed effect with values 0, 15, and 30.