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Table 1 Geometric mean hormone levels (ng/dL) for participants on 0 g alcohol and % change (Δ) in hormone levels from 0 g to 15 g and 30 g alcohol per day at weeks 4 and 8

From: The effects of moderate alcohol supplementation on estrone sulfate and DHEAS in postmenopausal women in a controlled feeding study

Hormone

 

0 g/d, mean (95% C.I.)

15 g/d, Δ (95% C.I.)*

30 g/d, Δ (95% C.I.)*

P-trend†

Estrone Sulfate

(4 wk)

47.5 (39.2–57.4)

6.9% (-4.2%–19.3%)

22.2% (9.4%–36.5%)

0.0006

 

(8 wk)

47.4 (40.5–55.6)

7.5% (-0.3%–15.9%)

10.7% (2.7%–19.3%)

0.009

DHEAS

(4 wk)

55.3 (47.0–65.1)

8.0% (4.5%–11.6%)

9.2% (5.6%–12.8%)

<0.0001

 

(8 wk)

59.4 (50.5–70.0)

5.1% (1.4%–9.0%)

7.5% (3.7%–11.5%)

0.0001

  1. * Estimates of percent change are from linear mixed models, including participant as a random effect and alcohol levels as fixed effects treated as two indicator variables.
  2. † P-trend values (two-sided) are from linear mixed models, including participant as a random effect and alcohol levels as a continuous fixed effect with values 0, 15, and 30.