Table 1 Baseline characteristics after randomization

Subjects, n

42

44

Age (year)

53.4 ± 8.1

52.6 ± 7.8

0.63

Men/women

15/27

17/27

0.83

Body weight (kg)

78.0 ± 13.3

76.0 ± 10.5

0.44

Body mass index (kg m¯ ² )

26.5 ± 3.3

26.3 ± 3.2

0.79

SBP (mmHg)

123 ± 14

128 ± 12

0.50

DBP (mmHg)

83 ± 9

81 ± 7

0.16

Plasma TG (mmol/L¯ ¹ )

1.4 ± 0.8

1.6 ± 0.8

0.32

Plasma cholesterol (mmol/L¯ ¹ )

6.4 ± 0.7

6.2 ± 0.8

0.36

Plasma LDL cholesterol (mmol/L¯ ¹ )

4.2 ± 1.0

4.0 ± 0.6

0.33

Plasma HDL cholesterol (mmol/L¯ ¹ )

1.5 ± 0.5

1.5 ± 0.4

0.28

LDL/HDL ratio

2.8 ± 1.0

2.9 ± 0.8

0.80

Plasma glucose (mmol/L¯ ¹ )

4.9 ± 0.6

4.9 ± 0.5

0.54

Insulin resistance (HOMA-IR)

1.3 ± 0.6

1.2 ± 0.6

0.47

Cathepsin S μg/L

18.3 ± 2.99

20.1 ± 4.1

0.02