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Table 5 Multivariable Regression Analysis of Follow-up Primary Outcome Measures (n=2,182) – Using Charlson Co-Morbidity Index as a Co-Variate

From: The impact of waist circumference on function and physical activity in older adults: longitudinal observational data from the osteoarthritis initiative

  

Waist

Circumference

Quartile

 
  

Low WC

25-50%ile

50-75%ile

75%+

Short-Form 12 Score

     

Overall Score

Overall

100.4 [98.3-102.5]

101.8 [100.7-102.8]

100.4 [99.4-101.4]

99.9 [98.8-101.0]

 

Δ

---

1.39

-0.02

-0.53

 

60-70

99.5 [95.1-103.8]

102.4 [101.0-103.9]

101.5 [100.2-102.7]

100.9 [99.6-102.2]

 

Δ

--

2.96

2.00

1.43

 

70+

100.7 [98.5-102.8]

100.8 [99.2-102.3]

98.5 [96.8-100.2]

98.2 [96.3-100.0]

 

Δ

--

0.08

-2.18

-2.53 (p=0.05)

Physical

Overall

46.8 [45.5-48.0]

46.8 [46.0-47.6]

45.6 [44.8-46.5]

45.2 [44.3-46.0]

 

Δ

---

0.02

-1.13

-1.60*

 

60-70

45.9 [43.5-48.3]

47.8 [46.7-48.9]

46.2 [45.1-47.3]

45.9 [44.7-47.1]

 

Δ

--

1.90

0.27

-0.02

 

70+

47.2 [45.7-48.7]

45.4 [44.1-46.7]

44.8 [43.5-46.1]

43.8 [42.4-45.1]

 

Δ

---

-1.84 (p=0.05)

-2.40 (p=0.015)

-3.47*

Mental

Overall

54.6 [53.7-55.4]

55.1 [54.4-55.8]

54.5 [53.8-55.2]

54.5 [53.7-55.3]

 

Δ

---

0.53

-0.02

-0.06

 

60-70

54.4 [53.0-55.8]

55.0 [54.1-55.9]

55.2 [54.3-56.0]

54.8 [53.8-55.8]

 

Δ

---

0.56

0.79

0.38

 

70+

54.5 [53.4-55.6]

55.2 [54.2-56.2]

53.5 [52.3-54.6]

54.4 [53.2-55.6]

 

Δ

---

0.70

-1.06

-0.14

Physical Activity Scale for Elderly

Overall

127.2 [121.2-133.2]

125.2 [119.8-130.6]

127.8 [121.5-134.1]

110.7 [104.7-116.6]

 

Δ

---

-2.04

0.55

-16.6*

 

60-70

132.6 [124.0-141.2]

136.7 [129.2-144.2]

136.3 [127.6-144.9]

122.5 [114.7-130.3]

 

Δ

---

3.09

3.67

-10.1

 

70+

116.4 [108.9-124.0]

108.6 [101.1-116.2]

113.6 [105.2-122.1]

93.2 [84.2-102.2]

 

Δ

---

-7.80

-2.80

-23.2*

Late-Life Disability Index

     

Frequency

Overall

55.5 [54.8-56.1]

55.1 [54.5-55.6]

55.3 [54.7-55.8]

55.1 [54.4-55.7]

 

Δ

---

-0.44

-0.25

-0.46

 

60-70

56.0 [55.1-56.9]

55.6 [54.8-56.4]

55.7 [54.9-56.5]

55.6 [54.8-56.4]

 

Δ

---

   
 

70+

54.7 [53.8-55.7]

54.3 [53.5-55.5]

54.5 [53.6-55.5]

54.2 [53.2-55.2]

 

Δ

--

-0.40

-0.28

-0.40

Limitation

Overall

82.2 [80.6-83.8]

82.3 [80.8-83.6]

79.6 [78.2-81.0] (p=0.02)

78.8 [77.3-80.3] (p=0.002)

 

Δ

---

0.05

-2.60

-3.4

 

60-70

83.0 [80.5-85.4]

83.9 [82.0-85.8]

81.0 [79.2-82.9]

80.5 [78.7-82.3]

 

Δ

---

0.97

-1.91

-2.42

 

70+

81.3 [78.9-83.6]

79.6 [77.4-81.7]

77.6 [75.4-79.8]

76.1 [73.5-78.7]

 

Δ

---

-1.70

-3.68 (p=0.02)

-5.16 (p=0.03)

Gait Speed

Overall

1.25 [1.22-1.29]

1.24 [1.22-1.26]

1.23 [1.22-1.25]

1.19 [1.17-1.21]

 

Δ

---

0.02

-0.02

-0.07*

 

60-70

1.25 [1.18-1.33]

1.27 [1.25-1.30]

1.26 [1.24-1.28]

1.23 [1.21-1.26]

 

Δ

---

0.02

0.04

-0.02

 

70+

1.23 [1.20-1.26]

1.18 [1.15-1.21]

1.19 [1.16-1.22]

1.12 [1.08-1.15]

 

Δ

---

-0.05 (p=0.019)

-0.04 (p=0.05)

-0.11*

  1. Values represent mean score (95% confidence interval) of the indicated metric adjusted for: Age, sex, education level, race, Charlson co-morbidity index, smoking status, knee OA, hip pain and cohort type (incident, progression or control), and baseline scoring (SF-12, PASE) where available. Values in 25-50%, 50-75%, high WC quartile columns represent difference from referent category (low WC). Models stratified by age adjust for the similar co-variates other than age.