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Table 3 Multivariable regression analysis of follow-up primary outcome measures (n = 2,182)

From: The impact of waist circumference on function and physical activity in older adults: longitudinal observational data from the osteoarthritis initiative

  

Waist

Circumference

Quartile

 
  

Low WC

25-50%ile

50-75%ile

75%+

Short-Form 12 Score

     

Overall Score

Overall

102.4 [101.0-103.9]

102.7 [101.5-103.9]

101.7 [100.7-102.8]

100.5 [99.2-101.8]

 

Δ

---

0.28

-0.69

-1.92 (p = 0.04)

 

60-70

102.9 [101.0-104.9]

103.0 [101.3-104.8]

102.5 [101.2-103.9]

101.4 [99.8-103.1]

 

Δ

---

0.10

-0.46

-1.50

 

70+

101.5 [99.0-104.0

102.1 [100.3-104.0]

100.3 [98.5-102.1]

99.1 [96.9-101.2]

 

Δ

---

0.62

-1.22

-2.45

Physical

Overall

47.9 [46.9-48.8]

47.6 [46.7-48.5]

46.7 [45.8-47.5]

45.5 [44.5-46.0]

 

Δ

---

-0.26

-1.20

-2.3 (p = 0.001)

 

60-70

47.8 [46.6-49.1]

48.7 [47.5-49.8]

47.0 [45.8-48.2]

46.2 [44.9-47.6]

 

Δ

---

0.83

-0.85

-1.61

 

70+

47.7 [46.0-49.4]

46.4 [45.0-47.9]

46.2 [44.9-47.5]

44.4 [42.9-46.0]

 

Δ

---

-1.26

-1.54

-3.26 (p = 0.004)

Mental

Overall

55.2 (54.4-55.9)

55.3 (54.5-56.1)

54.9 (54.2-55.7)

54.7 (53.8-55.5)

 

Δ

---

-0.39

0.16

-0.40

 

60-70

55.3 (54.3-56.2)

54.9 (53.8-55.9)

55.4 (54.5-56.4)

54.9 (53.8-56.0)

 

Δ

---

-0.39

0.16

-0.40

 

70+

54.9 (53.6-56.2)

55.6 (54.4-56.8)

54.3 (53.0-55.0)

54.5 (53.1-55.9)

 

Δ

---

0.71

-0.60

-0.37

Physical Activity Scale for Elderly

Overall

131.0 (124.3-137.7)

126.6 (120.3-132.8)

128.7 (121.5-135.9)

109.6 (102.6-116.6)

 

Δ

---

-4.47

-2.34

-21.4 (p < 0.001)

 

60-70

137.4 (127.8-146.9)

136.4 (12.7-145.1)

136.4 (126.7-146.2)

119.9 (111.1-128.7)

 

Δ

---

-1.0

-0.97

-17.5 (p = 0.006)

 

70+

117.5 (109.5-125.5)

112.2 (103.4-121.0)

114.6 (105.3-124.0)

93.5 (82.8-104.0)

 

Δ

---

-5.2

-2.83

-23.9 (p < 0.001)

Late-Life Disability Index

     

Frequency

Overall

56.0 (55.3-56.7)

55.6 (54.9-56.2)

55.9 (55.2-56.5)

55.1 (54.4-55.8)

 

Δ

---

-0.43

-0.17

-0.94

 

60-70

56.7 (55.8-57.6)

56.1 (55.1-57.0)

56.1 (55.2-57.8)

55.7 (54.8-56.6)

 

Δ

---

-0.66

-0.61

-1.1

 

70+

55.0 (54.0-56.0)

54.8 (53.9-55.8)

55.4 (54.4-56.5)

54.1 (53.0-55.2)

 

Δ

--

-0.20

0.43

-0.90

Limitation

Overall

83.3 (81.6-84.9)

83.2 (81.6-84.8)

81.8 (80.3-83.3)

79.2 (77.5-81.0)

 

Δ

--

-0.07

-1.47

-4.05 (p = 0.001)

 

60-70

84.2 (82.1-86.4)

84.6 (82.4-86.8)

83.2 (81.2-85.1)

80.9 (78.9-82.9)

 

Δ

--

0.38

-1.06

-3.3 (p = 0.026)

 

70+

81.8 (79.3-84.4)

81.1 (78.6-83.5)

80.0 (77.6-82.4)

76.3 (73.1-79.4)

 

Δ

---

-0.77

-1.86

-5.56 (p = 0.006)

Gait Speed

Overall

1.28 (1.26-1.31)

1.25 (1.23-1.27)

1.25 (1.23-1.26)

1.19 (1.17-1.22)

 

Δ

---

-0.03 (p = 0.018)

-0.04 (p = 0.06)

-0.09 (p < 0.001)

 

60-70

1.29 (1.26-1.32)

1.28 (1.25-1.31)

1.27 (1.24-1.29)

1.24 (1.21-1.27)

 

Δ

---

-0.02

-0.02

0.05 (p = 0.009)

 

70+

1.27 (1.23-1.31)

1.19 (1.15-1.23)

1.21 (1.17-1.24)

1.11 (1.07-1.16)

 

Δ

--

-0.08 (p = 0.002)

-0.06 (p = 0.015)

-0.15 (p < 0.001)

  1. Values represent mean score (95% confidence interval) of the indicated metric adjusted for: Age, sex, education level, race, modified Charlson co-morbidity index, smoking status, knee OA, hip pain and cohort type (incident, progression or control), and baseline scoring (SF-12, PASE) where available. Values in 25-50%, 50-75%, high WC quartile columns represent difference from referent category (low WC). Models stratified by age adjust for the similar co-variates other than age.
  2. Modified Charlson score consists of the following variables: chronic obstructive pulmonary disease, ulcers, renal disorders, kidney transplant, rheumatoid arthritis, and cancer.