Very low calorie diet without aspartame in obese subjects: improved metabolic control after 4 weeks treatment

Nutrition Journal

Table 4 Changes in metabolic variables; weight, blood pressure, glucose and lipids

All subjects
Variable	Inclusion	After diet, four weeks	P	N
Weight (kg)*	107.4 (99.6-115.1)	99.3 (92.1-106.4)	0.001	25
BMI (kg/m²)*	39.8 (38.0-41.6)	36.8 (35.1-38.6)	0.001	25
Excess weight*	40.2 (34.5-45.9)	32.1 (26.8-37.4)	0.001	25
SBP (mmHg)^§	150 (140–150)	135 (125–140)	0.005	25
DBP (mmHg)^§	85 (80–90)	90 (85–95)	0.04	25
Glucose (mmol/l)^§	5.6 (5.3-6.8)	4.8 (4.6-5.2)	0.001	24
HbA_1c (mmol/mol)^§	39 (37–44)	37 (35–43)	0.001	23
Cholesterol (mmol/l)^§	5.4 (4.9-6.2)	4.4 (4.1-4.9)	0.001	22
Triglycerides (mmol/l)^§	1.6 (1.1-2.2)	1.2 (1.1-1.6)	0.006	21
*Subjects with type 2 diabetes mellitus*
*Variable*	*Inclusion*	*After diet, four weeks*	P	N
Weight (kg)*	119.2 (99.3-139.1)	110.3 (91.5-129.1)	0.02	7
Glucose (mmol/l)^§	7.5 (7.0-12.5)	6.0 (4.8-6.8	0.02	7
HbA_1c (mmol/mol)^§	47 (44–66)	46 (45–59)	0.11	7

SBP = Systolic blood pressure. DBP = Diastolic blood pressure. *Presented as mean (95% confidence interval). ^§Presented as median (inter quartile range). P-value denotes the level of statistical significance in the difference between value at inclusion and after diet.

ISSN: 1475-2891