Effect of calcium phosphate and vitamin D3supplementation on bone remodelling and metabolism of calcium, phosphorus, magnesium and iron

Table 2 Mean intake of calcium, phosphorus, and vitamin D during defined diet in all study periods

Parameter	Supplements	Placebo	Interventions
Parameter	Supplements	Placebo	4 weeks	8 weeks
Calcium [mg/d]	CaP	938^b (197)	1998^a (192)¹	2014^a (194)¹
	Vitamin D₃	905 (187)	897 (219)²	916 (203)²
	CaP+vitamin D₃ ^t	889^b (154)	1913^a (151)¹	1872^a (164)¹
Phosphorous [mg/d]	CaP	1337^b (250)	1803^a (247)¹	1833^a (242)¹
	Vitamin D₃	1311 (236)	1303 (247)²	1324 (226)²
	CaP+vitamin D₃	1286^b (172)	1733^a (180)¹	1705^a (187)²
Vitamin D₃ [μg/d]	CaP	6.5 (0.6)	6.6 (0.6)¹	6.6 (0.5)¹
	Vitamin D₃	6.2^b (1.3)	15.2^a (1.0)²	15.2^a (1.0)²
	CaP+vitamin D₃	6.5^b (0.4)	15.1^a (0.4)²	15.1^a (0.3)²

n = 56; data are expressed as mean (standard deviation); CaP: tricalcium phosphate; ^{a b} mean values within a row with dissimilar superscript letters are significantly different (p ≤ 0.05); ^{1 2} mean values within a column with dissimilar superscript numbers are significantly different (p ≤ 0.05); results without superscripts in a row/column have no significant differences; effect of time was tested using general linear model with repeated measurements (with pairwise comparisons based on Fishers-LSD test); effect of supplementation was tested using univariate analysis of variance followed by Student-Newman-Keuls post hoc test.; ^t for statistical analysis the data were log₁₀ transformed, because of variance heterogeneity.

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