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Table 2 Plasma phospholipid fatty acid composition after control or ALA-rich diet for 6 months

From: Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo-controlled, parallel study

 

1.5 g/d ALA

9.5 g/d ALA

   
 

Male

Female

Male

Female

 

P value1

 
 

(n = 11)

(n = 10)

(n = 13)

(n = 10)

Sex

Diet

Sex*diet

 

(% total fatty acids)

   

16:0

26.7 ± 1.5

27.5 ± 1.4

28.0 ± 2.2

26.8 ± 1.3

0.82

0.44

0.073

18:0

13.2 ± 1.2

13.4 ± 1.5

12.5 ± 3.8

13.6 ± 1.6

0.82

0.84

0.20

22:0

1.4 ± 0.9

1.0 ± 0.5

1.3 ± 1.0

1.4 ± 1.1

0.11

0.50

0.69

18:1n-9

10.8 ± 3.0

10.9 ± 2.3

11.4 ± 2.9

11.2 ± 1.9

0.78

0.53

0.64

20:1n-9

0.4 ± 0.3

0.2 ± 0.1*

0.4 ± 0.2

0.3 ± 0.2

0.18

0.39

0.041

18:2n-6

22.2 ± 1.8

22.3 ± 2.4

22.1 ± 2.5

21.6 ± 2.6

0.55

0.58

0.61

18:3n-6

0.2 ± 0.2

0.2 ± 0.2

0.1 ± 0.1

0.2 ± 0.1

0.60

0.14

0.60

20:3n-6

3.6 ± 1.0

4.2 ± 1.3

3.5 ± 1.4

3.0 ± 1.6

0.97

0.38

0.12

20:4n-6

10.3 ± 2.4

10.0 ± 2.0

9.1 ± 2.7

8.8 ± 1.3

0.74

0.26

0.32

18:3n-3

0.3 ± 0.1

0.3 ± 0.2

0.6 ± 0.3

0.9 ± 0.3

0.19

<0.001

0.11

20:5n-3

1.5 ± 1.5

1.2 ± 1.0

1.5 ± 1.3

2.8 ± 1.7*

0.35

0.023

0.027

22:5n-3

2.0 ± 0.5

2.3 ± 0.7

2.5 ± 0.7

2.6 ± 0.7

0.11

0.22

0.39

22:6n-3

4.7 ± 1.2

3.9 ± 0.6

3.9 ± 1.3

3.7 ± 1.1

0.34

0.20

0.36

  1. Data are mean ± SD.
  2. 1Statistics were conducted using change from baseline data. *Significantly different from males in same dietary group (p < 0.05, independent mean t-test). Significant effect of diet within same sex (p < 0.05, independent mean t-test).