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Table 3 Stool fatty acid soaps (mg/g dry weight stool) at day 28

From: Stool fatty acid soaps, stool consistency and gastrointestinal tolerance in term infants fed infant formulas containing high sn-2 palmitate with or without oligofructose: a double-blind, randomized clinical trial

Primary fatty acid soap endpoints1 Feeding group Statistically significant group differences2
  Control sn-2 sn-2+OF HM  
(n =46) (n =51) (n =49) (n =48)
C16:0 FA soap (palmitate) 186.9 ± 48.8 159.3 ± 42.0 a 113.3 ± 43.1b, c 26.0 ± 26.2d a P =0.0028 vs. control
b P <0.0001 vs. control
Total FA soaps 272.8 ± 67.9 251.4 ± 65.1 175.6 ± 64.1b, c 63.5 ± 56.3d c P <0.0001 vs. sn-2
d P <0.0001 vs. all formulas
Secondary endpoints - individual FA soaps1, 3      
C12:0 FA soap (lauric) 4.6 ± 2.0 3.2 ± 1.4 1.6 ± 1.4 0.3 ± 0.4  
C14:0 FA soap (myristic) 13.7 ± 4.5 9.6 ± 3.0 6.0 ± 3.2 1.3 ± 1.5  
C18:0 FA soap (stearic) 37.8 ± 8.7 38.6 ± 9.8 31.4 ± 10.5 23.2 ± 20.5  
C18:1 FA soap (oleic) 20.0 ± 8.7 29.3 ± 9.9 15.5 ± 10.5 8.4 ± 8.8  
C18:2 FA soap (linoleic) 3.2 ± 1.6 3.4 ± 1.4 1.8 ± 1.7 1.6 ± 1.6  
  1. 1Mean ± SD.
  2. 2Based on analysis of variance followed by pairwise comparisons for formula groups, and independent t-tests for each of the formula groups vs. HM group.
  3. 3Descriptively summarized; no statistical analysis done.
  4. Control = bovine milk-based, whey-predominant, alpha-lactalbumin-enriched term infant formula with 100% vegetable fat blend; FA = fatty acid; HM = human milk; sn-2 = high sn-2 palmitate formula (Control formula modified to contain 60% vegetable fat blend and 40% high sn-2 palmitate fat blend); sn-2+OF = high sn-2 palmitate formula supplemented with oligofructose at 3.0 g/L.
  5. Statistical significance: a: P =0.0028 vs. control, b: P <0.0001 vs. control, c: P <0.0001 vs. sn-2 and d: P <0.0001 vs. all formulas.