Consumption of a dietary portfolio of cholesterol lowering foods improves blood lipids without affecting concentrations of fat soluble compounds

Table 3 Effect of portfolio and control diets on blood lipids levels and the differences between dietary interventions

	Treatments^a						Between treatment differences^b
Variable	Portfolio intensive (n = 101)		Portfolio routine (n = 122)		Control (n = 122)		PI vs. PR		PI vs. C		PR vs. C
	Wk 0	Wk 24	Wk 0	Wk 24	Wk 0	Wk 24	Mean (95% CI)	P-value	Mean (95% CI)	P-value	Mean (95% CI)	P-value
Cholesterol, mmol/L
Total	6.53	5.88	6.63	6.04	6.46	6.41	-0.07 (-0.31, 0.17)	0.777	-0.56 (-0.80, -0.33)	<0.0001	-0.49 (-0.73, -0.26)	<0.0001
LDL-C	4.42	3.80	4.50	3.92	4.35	4.24	-0.06 (-0.27, 0.15)	0.773	-0.46 (-0.67, -0.26)	<0.0001	-0.40 (-0.60, -0.20)	<0.0001
HDL-C	1.42	1.39	1.40	1.39	1.39	1.40	0.007 (-0.006, 0.072)	0.965	-0.02 (-0.09, 0.04)	0.619	-0.03 (-0.09, 0.03)	0.453
Triglycerides	1.52	1.50	1.61	1.60	1.66	1.72	-0.06 (-0.23, 0.12)	0.743	-0.10 (-0.27, 0.07)	0.372	-0.04 (-0.21, 0.13)	0.824
Total:HDL-C	4.81	4.44	5.01	4.60	4.93	4.87	-0.05 (-0.27, 0.17)	0.852	-0.33 (-0.54, -0.11)	0.001	-0.28 (-0.50, -0.06)	0.008
Apolipoproteins g/L
A1	1.60	1.60	1.60	1.60	1.60	1.59	0.02 (-0.02, 0.06)	0.533	0.01 (-0.03, 0.05)	0.868	-0.01 (-0.05, 0.03)	0.819
B	1.23	1.10	1.26	1.14	1.20	1.20	-0.01 (-0.06, 0.03)	0.846	-0.11 (-0.16, -0.07)	<0.0001	-0.10 (-0.15, -0.06)	<0.0001

^aFor paired samples T-test of change from baseline, done on absolute change values.
^bUsing analysis of covariance with sex, treatment and sex by treatment interaction as main effects and baseline as a covariate. A Tukey adjustment was made for multiple comparisons. Abbreviations: PI Portfolio intensive, PR Portfolio routine, C Control.

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