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Figure 4 | Nutrition Journal

Figure 4

From: P38MAP kinase, but not phosphoinositol-3 kinase, signal downstream of glutamine-mediated fibronectin-integrin signaling after intestinal injury

Figure 4

Proposed working model. GLN is protective in IEC-6 cells by activating PI3-K signaling which prevents FN expression and increases HSP70 expression after thermal injury. Furthermore, GLN is protective by dephosphorylating p38MAPK via GLN-mediated FN-Integrin signaling after HS. GLN-mediated PI3-K/Akt signaling, however, seems to be independent of FN-Integrin signaling.

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Nutrition Journal

ISSN: 1475-2891

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