Behavioral response to green tea and placebo in healthy subjects. (A) MADRS and (B) HRSD-17 total scores were reduced by chronic treatment with green tea for 5 weeks. Data are expressed as mean ± SEM. Differences between green tea (n = 24) and placebo (n = 22) were assessed using Student’s t test. *p < 0.05, **p < 0.01, ***p < 0.001 compared with placebo. MADRS, Montgomery-Asberg Depression Rating Scale; HRSD-17, 17-item Hamilton Rating Scale for Depression.