Table 2 Serum lipids and other atherogenic and inflammatory risk markers
Parameter | Baseline mean (SD) | Change at week 8 | 95% CI | P-value | Change at week 16 | 95% CI | P-value |
|---|---|---|---|---|---|---|---|
Total-C (mg/dl)a | 205.56 (44.10) | -5.96 | -15.19 to 3.27 | 0.2005 | -15.92 | -25.15 to -6.69 | 0.0011 |
LDL-C (mg/dl)a | 124.52 (38.20) | -2.96 | -9.84 to 3.92 | 0.3912 | -10.52 | -17.40 to -3.64 | 0.0035 |
HDL-C (mg/dl)a | 52.04 (10.83) | -1.96 | -5.48 to 1.56 | 0.2683 | 0.32 | -3.20 to 3.84 | 0.8557 |
Atherogenic Index | 4.08 (1.08) | 0.02 | -0.25 to 0.28 | 0.8940 | -0.36 | -0.62 to -0.09 | 0.0095 |
TAG (mmol/l) | 1.42 (0.66) | 0.22 | -0.17 to 0.61 | 0.2586 | -0.24 | -0.63 to 0.15 | 0.2191 |
Apolipoprotein A1 (g/l) | 1.50 (0.25) | 0.05 | -0.04 to 0.14 | 0.3073 | 0.02 | -0.07 to 0.11 | 0.7086 |
hsCRP (mg/l) | 1.86 (2.03) | -0.11 | -1.05 to -0.83 | 0.8159 | 0.86 | 0.08 to 1.81 | 0.0729 |
Homocysteine (μmol/l) | 8.51 (3.14) | -2.88 | -3.61 to -2.14 | <0.0001 | -3.25 | -3.98 to -2.51 | <0.0001 |
Methionine (μmol/l) | 28.55 (4.32) | -5.13 | -7.14 to -3.13 | <0.0001 | -8.58 | -10.59 to -6.57 | <0.0001 |
Cysteine (μmol/l) | 173.87 (33.25) | 44.00 | 25.98 to 62.03 | <0.0001 | 36.37 | 18.34 to 54.39 | 0.0002 |
Lipoprotein Subfractions (mg/dl) a | |||||||
VLDL | 28.84 (6.34) | -1.08 | -3.86 to 1.70 | 0.4378 | -5.48 | -8.26 to -2.70 | 0.0002 |
IDL-1 | 28.48 (10.02) | -1.88 | -4.40 to 0.64 | 0.1399 | -5.20 | -7.72 to -2.68 | 0.0001 |
IDL-2 | 11.12 (4.21) | -0.12 | -1.25 to 1.01 | 0.8322 | -2.08 | -3.21 to -0.95 | 0.0006 |
IDL-3 | 16.40 (7.71) | 3.04 | 0.31 to 5.77 | 0.0297 | -1.08 | -3.81 to 1.65 | 0.4299 |
LDL-1 | 47.60 (14.78) | 0.48 | -3.80 to 4.76 | 0.8226 | 1.28 | -3.00 to 5.56 | 0.5505 |
LDL-2 | 19.60 (13.44) | -4.68 | -7.84 to -1.52 | 0.0045 | -3.44 | -6.60 to -0.28 | 0.0335 |
LDL-3 | 1.32 (1.93) | -0.08 | -1.02 to 0.86 | 0.8642 | 0.00 | -0.94 to 0.94 | 1.0000 |