Diurnal variation of phenylalanine and tyrosine concentrations in adult patients with phenylketonuria: subcutaneous microdialysis is no adequate tool for the determination of amino acid concentrations

Table 2 Short-term effect of meals on mean phenylalanine and tyrosine concentrations and the phenylalanine: tyrosine concentration ratio in serum

Phe = phenylalanine; Tyr = tyrosine; [Phe]/[Tyr] = phenylalanine: tyrosine concentration ratio.
^aExcept for breakfast: n = 7 and therefore denominator df = 5.
To evaluate the short-term effect of meals on phenylalanine and tyrosine concentrations and the phenylalanine: tyrosine concentration ratio in serum repeated-measures MANOVA were performed with the within-subjects factor “time of measurement” (before the meal, 60 min after the meal, 120 min after the meal).

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