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Table 3 Biopharmaceutics Classification System of medications [31]

From: Thickening agents used for dysphagia management: effect on bioavailability of water, medication and feelings of satiety

  High solubility Low solubility
High permeability Class I Class II
High solubility Low solubility
High permeability High permeability
Transporter effects minimal Efflux (flows out) transporter effects predominate
Examples: Atropine, Caffeine, Diazepam, Glucose, Levodopa, Prednisolone Examples: Digoxin, Ibuprofen, Warfarin
Low permeability Class III Class IV
High solubility Low solubility
Low permeability Low permeability
Absorptive transporter effects predominate Absorptive and efflux transporter effects could be important
Examples: Atenolol, Captopril, Cimetidine, Acyclovir, Penicillin, Amoxicillin, Erythromycin Examples: Amphotericin B, Chlothalidone, Neomycin