Table 5 Acute changes in methylxanthine concentrations after single-dose chocolate intake
Low-flavanol | High-flavanol | Pvalue of change between treatments | |
|---|---|---|---|
chocolate | chocolate | ||
(n = 21) | (n = 23) | ||
Theobromine (μg/mL) | |||
0 min (baseline) | 0.35 ± 0.37 | 0.45 ± 0.43 | - |
180 min | 5.47 ± 1.29 | 6.51 ± 0.80 | 0.0122 |
P value (180 vs. 0 min) | <0.0001 | <0.0001 | |
Theophylline (μg/mL) | |||
0 min (Baseline) | 0.07 ± 0.11 | 0.13 ± 0.18 | - |
180 min | 0.12 ± 0.12 | 0.18 ± 0.13 | 0.85 |
P value (180 vs. 0 min) | <0.0001 | 0.0009 | |
Caffeine (μg/mL) | |||
0 min (Baseline) | 0.29 ± 0.46 | 0.58 ± 0.82 | - |
180 min | 1.07 ± 0.50 | 1.54 ± 0.67 | 0.0201 |
P value (180 vs. 0 min) | <0.0001 | <0.0001 |