A randomized trial of fish oil omega-3 fatty acids on arterial health, inflammation, and metabolic syndrome in a young healthy population

Table 3 Effect of fish oil supplementation on arterial measures*

Markers	Placebo		Omega-3		Treatment difference	S.E. of difference	P-value of difference
Markers	Before	After	Before	After	Treatment difference	S.E. of difference	P-value of difference
Aortic systolic blood pressure (mmHg)	112.1	110.0	110.8	111.1	+2.54	1.70	0.91
Central PWV (m/s)	7.44	6.61	7.49	7.43	+0.76	0.70	0.26
Augmentation Index (%)	10.8	7.4	10.9	11.6	+4.00	2.73	0.47
SBP (mmHg)	125.7	124.5	124.5	125.1	+1.9	1.7	0.26
LDL cholesterol (mmol/L)	2.41	2.39	2.47	2.48	-0.01	0.15	0.81
Triglycerides (mmol/L)	0.88	0.99	0.91	0.91	-0.099	0.145	0.83
HDL-cholesterol (mmol/L)	1.225	1.164	1.204	1.189	+0.004	0.050	0.74
TNF-α (pg/mL)	4.90	4.52	5.31	5.70	+0.14	0.08	0.75
IL-6 (pg/mL)	0.87	0.77	0.99	1.12	+0.21	0.19	0.51
CRP (nmol/L)	20.7	21.8	17.3	18.7	+0.12	0.34	0.53

* Repeated measure general linear models. PWV = Central pulse wave velocity, BMI = Body Mass Index, SBP = Systolic Blood Pressure. TNF-α = Tumor Necrosis Factor-α, IL-6 = Interleukin-6, CRP = C - reactive protein. Triglycerides, TNF-α, IL-6, and CRP are log transformed; means expressed as geometric means; differences are expressed as log values.

ISSN: 1475-2891