Table 3 Genotypes and alleles frequencies of the C667T and A1298C ( MTHFR ) polymorphisms in NAFLD patients and control subjects and statistical parameters
From: Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)
Genotypes and alleles | NAFLD N (35) % | P * | Control N (45)% | P ** | χ2 | P *** |
|---|---|---|---|---|---|---|
MTHFR C677T | ||||||
CC | 12 (34.29) | 0.996 | 23 (51.11) | 0.360 | 0.154 | 0.345 |
CT | 17 (48.57) | 20 (44.45) | ||||
TT | 06 (17.14) | 02 (4.44) | ||||
CT+TT | 23 (63.71) | 22 (36.30) | ||||
Allele 677C | 21 (0.58) | 33 (0.73) | ||||
Allele 677T | 14 (0.41) | 12 (0.26) | ||||
MTHFR A1298C | ||||||
AA | 20 (57.15) | 0.106 | 26 (57.79) | 0.707 | 1.727 | 0.473 |
AC | 15 (42.85) | 17 (37.77) | ||||
CC | 0 | 02 (4.44) | ||||
AC+CC | 15 (50.31) | 19 (49.68) | ||||
Allele 1298A | 24 (0.78) | 35 (0.76) | ||||
Allele 1298C | 4 (0.21) | 10 (0.23) | ||||