Double-blind placebo-controlled food challenges in children with alleged cow’s milk allergy: prevention of unnecessary elimination diets and determination of eliciting doses

Table 3 The 116 successful tests

Reaction	Children		Conclusion	Reintroduction
	Number	Percentage
No reaction to both feedings	55	47	No CMA	A: 49
				B: 2
				C: 2
				D: 1
				E: 1
Comparable reaction after both feedings	4	3	No CMA	A: 2
				C: 1
				D: 1
Acute reaction after placebo feeding (vomiting)	1	1	No CMA	A: 1
Late reaction after placebo feeding	14	12	No CMA	A: 8
				D: 5
				E: 1
Acute and late reaction after placebo feeding	2	2	No CMA	D: 2
Objective acute reaction after placebo feeding alone	2	2	CMA; interpreted as accidentally exchanged placebo and verum feedings by treating physician
Acute reaction after verum feeding	12	10	CMA
Late reaction after verum feeding	15	13	CMA
Acute and late reaction after verum feeding	11	10	CMA

CMA, cow’s milk allergy; A, successful reintroduction; B, parents refused to reintroduce cow’s milk; C, reintroduction stopped without medical advice; D, reintroduction stopped with medical advice; E: no information available on reintroduction.

ISSN: 1475-2891