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Table 3 Lipid coronary heart disease risk factor changes during the 12-week study

From: Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial

  Intervention Week 11 Week 12 P-value2 P-value3 Change4 P-value5
Total cholesterol (mg/dl) ADF 201 ± 9 175 ± 12 <0.01 0.12 -26 ± 6 0.50
  Control 211 ± 11 202 ± 9 0.54   -9 ± 5  
LDL cholesterol (mg/dl) ADF 118 ± 9 99 ± 9 0.01 0.82 -18 ± 6 0.29
  Control 128 ± 10 119 ± 6 0.08   -9 ± 4  
HDL cholesterol (mg/dl) ADF 56 ± 3 54 ± 4 0.49 0.77 -2 ± 3 0.51
  Control 57 ± 2 58 ± 4 0.83   1 ± 2  
Triacylglycols (mg/dl) ADF 109 ± 13 87 ± 9 0.06 0.01 -22 ± 11 0.22
  Control 108 ± 18 118 ± 19 0.34   10 ± 7  
Non-HDL cholesterol (mg/dl) ADF 149 ± 11 124 ± 12 <0.01 0.54 -25 ± 5 0.96
  Control 153 ± 12 144 ± 10 0.79   -9 ± 5  
LDL particle size (Å) ADF 254 ± 1 258 ± 2 <0.01 <0.01 4 ± 1 0.13
  Control 252 ± 2 250 ± 3 0.16   -2 ± 1  
  1. Values reported as mean ± SEM. ADF: Alternate day fasting.
  2. 1Baseline values were not significantly different between intervention groups for any parameter: Independent samples t-test.
  3. 2P-value between week 1 and week 12: Paired t-test.
  4. 3P-value between groups at week 12: Independent samples t-test.
  5. 4Absolute change between week 1 and week 12 values.
  6. 5P-value between groups for absolute change: Independent samples t-test.
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