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Table 3 OR and 95% CI of hyperhomocysteinemia and hypercysteinemia by quartiles of different dietary protein intake

From: Dietary protein and plasma total homocysteine, cysteine concentrations in coronary angiographic subjects

 

Hyperhomocysteinemiaa

Hypercysteinemiaa

Q1

Q2

Q3

Q4

Q1

Q2

Q3

Q4

n

253

254

254

254

253

254

254

254

Total protein intake

        

Crude OR (95% CI)b

1

1.20(0.84-1.71)

1.30(0.91-1.85)

1.94(1.36-2.77)**

1

1.20(0.70-2.06)

1.60(0.96-2.68)

1.78(1.07-2.96)*

Adjusted OR (95% CI)c

1

1.30(0.89-1.91)

1.37(0.94-1.99)

2.13(1.45-3.12)**

1

1.16(0.66-2.04)

1.67(0.97-2.86)

1.73(1.03-2.92)*

Adjusted OR (95% CI)d

1

1.48(0.98-2.25)

1.57(1.02-2.41)*

2.63(1.70-4.07)**

1

1.14(0.64-2.03)

1.56(0.89-2.75)

1.69(1.02-2.87)*

Animal protein intake

        

Crude OR (95% CI)b

1

1.46(1.01-2.10)*

1.79(1.25-2.58)*

3.32(2.30-4.79)**

1

1.27(0.76-2.13)

1.34(0.80-2.24)

1.50(0.91-2.49)

Adjusted OR (95% CI)c

1

1.51(1.03-2.22)*

1.87(1.27-2.75)*

3.73(2.52-5.54)**

1

1.28(0.74-2.21)

1.45(0.84-2.51)

1.59(0.93-2.70)

Adjusted OR (95% CI)d

1

1.56(1.03-2.38)*

2.01(1.31-3.08)*

4.14(2.67-6.43)**

1

1.34(0.77-2.36)

1.51(0.85-2.68)

1.60(0.91-2.80)

Plant protein intake

        

Crude OR (95% CI)b

1

0.77(0.54-1.10)

0.51(0.35-0.72)**

0.46(0.32-0.66) **

1

1.01(0.62-1.62)

0.91(0.55-1.48)

0.88(0.53-1.44)

Adjusted OR (95% CI)c

1

0.77(0.53-1.10)

0.54(0.37-0.79)*

0.47(0.32-0.68)**

1

1.11(0.66-1.86)

1.02(0.61-1.70)

0.90(0.53-1.51)

Adjusted OR (95% CI)d

1

0.76(0.51-1.13)

0.63(0.41-0.96)*

0.59(0.38-0.91)*

1

1.28(0.73-2.26)

1.12(0.64-1.93)

0.96(0.56-1.64)

  1. aCut-off points are > 16 μmol/L for plasma homocysteine and > 300 μmol/L for plasma cysteine.
  2. bValues are OR (95% CI) from logistic regression.
  3. cValues are OR (95% CI) from logistic regression adjusted for age, sex, total energy intake, total fat intake, and BMI.
  4. dValues are OR (95% CI) from logistic regression adjusted for age, sex, total energy intake, total fat intake, BMI, smoking, alcohol use, tea use, hypertension, diabetes, folate, PLP, vitamin B12, HDL, LDL, and creatinine. Asterisks indicate difference from lowest quartiles of different dietary protein intake. * P < 0.05, ** P < 0.001.