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Table 2 Changed levels of coenzyme Q10, vitamin E, antioxidant enzymes activities, and inflammatory markers after supplementation

From: Effects of coenzyme Q10 supplementation (300 mg/day) on antioxidation and anti-inflammation in coronary artery disease patients during statins therapy: a randomized, placebo-controlled trial

 

Placebo (n = 19)

Q10-300 (n = 23)

Pvalues1

Coenzyme Q10 (μmol/L)

−0.01 ± 0.09 (-0.03)

1.10 ± 0.54 (1.26)

< 0.001b

Coenzyme Q10/TC (μmol/mmol)

−0.01 ± 0.07 (-0.00)

0.25 ± 0.11 (0.25)

< 0.001b

Vitamin E (μmol/L)

−3.35 ± 4.51 (-3.08)

−0.29 ± 4.03 (-0.83)

0.046b

Vitamin E/TC (μmol/mmol)

−0.88 ± 1.45 (-0.55)

0.07 ± 1.08 (0.11)

0.032a

SOD (U/mg protein)

1.63 ± 21.54 (3.63)

15.90 ± 20.48 (12.91)

0.034a

CAT (U/mg protein)

−1.42 ± 8.26 (-1.18)

6.17 ± 11.28 (3.18)

0.033b

GPx (U/mg protein)

0.91 ± 3.70 (-0.24)

4.62 ± 6.52 (2.15)

0.042b

CRP (mg/L)

0.39 ± 1.24 (0.00)

−0.20 ± 0.73 (0.00)

0.343b

TNF-α (pg/mL)

0.17 ± 0.77 (0.08)

−0.30 ± 0.35 (-0.26)

0.036b

IL-6 (pg/mL)

0.08 ± 0.64 (-0.11)

−0.52 ± 0.79 (-0.14)

0.040a

Adiponectin (μg/mL)

0.36 ± 2.89 (0.30)

0.19 ± 1.88 (-0.20)

0.71b

  1. Data are mean ± SD (median).
  2. 1values are significantly different between the placebo and the Q10-300 groups.
  3. adata were analyzed by the Student’s t-test.
  4. bdata were analyzed by the Mann-Whitney rank sum test.
  5. CAT, catalase; CRP, C-reactive protein; GPx, glutathione peroxidase; IL-6, interleukin-6; SOD, superoxide dismutase; TC, total cholesterol; TNF-α, tumor necrosis factor-α.
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Nutrition Journal

ISSN: 1475-2891

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