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Table 3 Laboratory values after treatment

From: Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients - a randomized double-blind placebo-controlled pilot study

Laboratory measurement

Reference value

Probiotic cheese

Control cheese

Extent of changes

  

Baseline

After treatment

P

Baseline

After treatment

P

Probiotic vs. Control

P

Total cholesterol, mmol/L

<5.2

5.32 ± 1 25

4.09 ± 1.20

<0.001

5.34 ± 0.95

4.35 ± 0.87

0.004

0.495

LDL, mmol/L

< 3.8

3.08 ± 1.11

2.20 ± 0.92

0.004

3.21 ± 0.69

2.64 ± 0.66

0.021

0.276

HDL, mmol/L

< 1.15

1.13 ± 0.25

0.94 ± 0.17

0.006

1.14 ± 0.26

1.05 ± 0.22

0.229

0.128

TG, mmol/L

< 1.7

2.80 ± 2.01

2.09 ± 1.62

0.041

2.14 ± 1.16

1.43 ± 0.56

0.085

0.696

Serum glucose, mmol/L

3.9 -5.8

7.16 ± 2.84

5.87 ± 1.00

0.171

6.84 ± 1.92

5.64 ± 1.6

0.014

0.875

Serum creatinine, μmol/L

50 – 105

80.8 ± 20.0

69.2 ± 19.4

0.003

70.5 ± 13.6

57.3 ± 7.4

0.007

0.394

Urea, μmol/L

2.5 – 6.4

4.72 ± 1.21

5.62 ± 2.29

0.017

4.66 ± 2.71

3.89 ± 0.98

0.245

0.011

Uric acid, μmol/L

200 – 340

356.1 ± 85.7

393.4 ± 128.6

<0.07

326.7 ± 147.7

308.8 ± 111.4

0.49

0.252

Total bilirubin, μmol/L

< 20

14.9 ± 5.68

12.6 ± 4.24

0.003

14.2 ± 4.83

11.3 ± 3.61

0.005

0.547

AST, U/L

0 – 35

23.5 ± 8.02

27.8 ± 9.86

<0.053

31.5 ± 16.6

25.0 ± 10.5

0.084

0.468

ALT, U/L

0 – 35

32.8 ± 16.0

36.3 ± 20.9

0.390

45.3 ± 36.4

35.9 ± 26.1

0.149

0.118

  1. ALT, alanine aminotransferase; AST, aspartate aminotransferase; HDL, high-density lipoprotein;
  2. LDL, low-density lipoprotein; TG, triglycerides.