Skip to main content

Table 5 Plasma concentrations of blood lipids, hs-CRP, and urea at baseline and changes after 4 wk and 8 wk of intervention with LPI and MPI

From: Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol ratio in hypercholesterolemic adults after four weeks of supplementation: a randomized, controlled crossover study

  

LPI

MPI

  
  

Changes from baseline

Changes from baseline

P a

P a

 

Baseline

wk 4

wk 8

wk 4

wk 8

wk 4

wk 8

Total cholesterol (mmol/L)

6.54 ± 1.14

−0.12 ± 0.48

−0.05 ± 0.44

−0.22 ± 0.63

0.02 ± 0.49

0.36

0.52

LDL cholesterol (mmol/L)

4.38 ± 1.14

−0.26 ± 0.53**

−0.08 ± 0.50

−0.32 ± 0.54**

−0.06 ± 0.34

0.47

0.90

HDL cholesterol (mmol/L)

1.46 ± 0.45

0.04 ± 0.15

−0.05 ± 0.19

−0.03 ± 0.18

−0.02 ± 0.13

0.036

0.20

Triacylglyceroles (mmol/L)

1.77 ± 1.17

0.08 ± 0.59

0.19 ± 0.45*

0.17 ± 0.70

0.16 ± 0.77

0.59

0.77

LDL:HDL cholesterol ratio

3.32 ± 1.39

−0.29 ± 0.53**

0.02 ± 0.53

−0.20 ± 0.62

−0.05 ± 0.39

0.34

0.29

hs-CRPb, c (mg/L)

1.93 ± 2.12

−0.23 ± 1.29

−0.28 ± 1.38

−0.09 ± 1.17

−0.32 ± 1.41

0.63

0.89

Urea (mmol/L)

4.98 ± 1.30

0.59 ± 0.94***

0.47 ± 1.10*

0.78 ± 1.19***

0.44 ± 1.06*

0.36

0.86

  1. Values are presented as means ± standard deviation, n = 33.
  2. Abbreviation: LPI lupin protein isolate, MPI milk protein isolate, hs-CRP high-sensitivity C-reactive protein.
  3. a P-value is for differences between treatments at wk 4 or at wk 8 determined by repeated measures ANOVA.
  4. bData were not normally distributed and/or had heterogeneous variances, and thus were statistically analyzed using a linear mixed model.
  5. c n = 23, hs-CRP values of some participants had to be excluded due to a temporary inflammatory status at time of measurement.
  6. *, **, ***Significant differences comparing wk 4 and wk 8 with baseline determined by repeated measures ANOVA (* P ≤ 0.050, ** P ≤ 0.010, *** P ≤ 0.001).