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Table 4 Concentration and daily excretion of short-chain fatty acids (SCFA) in faeces

From: Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial

 

BG (n = 26)

WG (n = 24)

SG (n = 26)

 

Run-in

Blue lupin

Citrus

Run-in

White lupin

Citrus

Run-in

Soya

Citrus

Faecal concentration [μmol/g faeces]

Total SCFA

62.9 ± 23.3b

75.4 ± 24.0a

65.3 ± 24.2b

69.4 ± 23.0

75.0 ± 21.4

72.4 ± 22.6

77.1 ± 21.1

81.3 ± 19.7

75.7 ± 23.5

Acetate

37.3 ± 13.1b

45.6 ± 12.3a

41.2 ± 15.9ab

41.5 ± 12.8

45.9 ± 12.5

45.0 ± 13.6

46.5 ± 12.4

49.6 ± 12.7

46.1 ± 14.4

Propionate

9.86 ± 4.73b

11.9 ± 5.0a

9.05 ± 3.89b

10.7 ± 5.3

11.9 ± 4.6

10.3 ± 4.3

13.2 ± 6.6ab

15.0 ± 4.9a

12.2 ± 5.5b

iso -Butyrate

1.11 ± 0.45

0.97 ± 0.55

0.91 ± 0.49

1.49 ± 0.59a

1.25 ± 0.51b

1.15 ± 0.52b

1.25 ± 0.56a

1.21 ± 0.63a

0.95 ± 0.38b

n -Butyrate

11.4 ± 6.5ab

14.0 ± 8.4a

11.3 ± 6.4b

11.0 ± 5.3

12.3 ± 6.3

11.9 ± 5.4

12.6 ± 5.1

12.1 ± 4.4

13.3 ± 6.3

iso -Valerat

1.76 ± 0.70a

1.46 ± 0.78b

1.47 ± 0.79b

2.14 ± 0.89a

1.69 ± 0.90b

1.57 ± 0.77b

1.70 ± 0.88a

1.58 ± 1.02ab

1.28 ± 0.58b

n -Valerat

1.17 ± 0.57

1.18 ± 0.60

0.98 ± 0.53

1.54 ± 0.72

1.41 ± 0.58

1.40 ± 0.61

1.29 ± 0.73

1.21 ± 0.78

1.14 ± 0.67

n -Caproate W

0.26 ± 0.44b

0.30 ± 0.42ab

0.39 ± 0.50a

0.52 ± 0.67b

0.60 ± 0.57ab

0.99 ± 1.24a

0.58 ± 0.74

0.58 ± 0.77

0.66 ± 078

Daily excretion [mmol/d]

Total SCFA

8.89 ± 6.30b

14.1 ± 9.5a

12.0 ± 10.0a

7.68 ± 5.78b

11.7 ± 9.1a

10.9 ± 7.2a

11.0 ± 6.8

12.9 ± 7.1

12.9 ± 6.5

Acetate

5.20 ± 3.53b

8.57 ± 5.95a

7.49 ± 6.18a

4.61 ± 3.49b

7.09 ± 5.50a

6.68 ± 4.10a

6.63 ± 4.23

7.96 ± 4.61

7.86 ± 4.13

Propionate

1.44 ± 1.20b

2.25 ± 1.61a

1.75 ± 1.70b

1.25 ± 1.08b

1.84 ± 1.47a

1.61 ± 1.38ab

1.91 ± 1.47

2.35 ± 1.25

2.11 ± 1.22

iso -Butyrate

0.15 ± 0.08

0.15 ± 0.09

0.13 ± 0.08

0.14 ± 0.07

0.16 ± 0.09

0.16 ± 0.11

0.16 ± 0.09

0.17 ± 0.10

0.16 ± 0.08

n -Butyrate

1.69 ± 1.45b

2.71 ± 2.35a

2.24 ± 2.21a

1.27 ± 1.15b

2.09 ± 2.01a

1.89 ± 1.48a

1.80 ± 1.28b

1.90 ± 1.24b

2.28 ± 1.48a

iso -Valerat

0.22 ± 0.11

0.22 ± 0.12

0.20 ± 0.10

0.20 ± 0.10

0.21 ± 0.12

0.21 ± 0.13

0.21 ± 0.12

0.21 ± 0.11

0.21 ± 0.10

n -Valerat

0.16 ± 0.13

0.19 ± 0.13

0.16 ± 0.13

0.16 ± 0.10

0.19 ± 0.11

0.20 ± 0.15

0.18 ± 0.13

0.18 ± 0.14

0.19 ± 0.13

n -Caproate W

0.04 ± 0.08b

0.04 ± 0.06ab

0.05 ± 0.09a

0.05 ± 0.07b

0.08 ± 0.10ab

0.15 ± 0.22a

0.08 ± 0.11b

0.09 ± 0.13ab

0.11 ± 0.15a

  1. Values are presented as mean ± standard deviation.
  2. BG blue lupin group, WG white lupin group, SG soya group; blue lupin, Lupinus angustifolius cv. Boregine; white lupin, Lupinus albus cv. Typ Top; soya, Glycine max cv. Hefeng; citrus, citrus fibre Herbacel AQ Plus serving as active comparator.
  3. a>b>cSignificant differences between mean values within each group with unequal superscript letters (P ≤ 0.05) determined by repeated measures ANOVA.
  4. WValues were not normally distributed; significance was calculated by means of the Wilcoxon test.