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Table 3 Changes in energy balance, physical activity index, MS parameters and body composition during the residential programme and follow-up for the two groups of protein intake (PI): Normal (NPI) and High (HPI) with respectively a PI at 1.0 g/kg/day and 1.2 g/kg/day

From: Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial

Variable

Groups

D0

D20

D90

D180

Body composition measured by DEXA:

    

Weight (kg)

NPI

90.3 ± 11.6

86.5 ± 11.0

84.4 ± 11.1†‡

85.4 ± 12.1†‡

 

HPI

94.1 ± 15.2

90.7 ± 14.5

87.1 ± 13.6†‡

86.4 ± 15.0†‡

BMI (kg/m2)

NPI

32.1 ± 4.2

30.7 ± 3.8

29.9 ± 3.5†‡

30.3 ± 3.7†‡

 

HPI

35.2 ± 4.2

33.9 ± 4.1

32.6 ± 4.3†‡

32.4 ± 4.7†‡

Lean (kg)

NPI

58.287 ± 7.47

57.323 ± 7.56

56.488 ± 7.89

56.798 ± 7.99

 

HPI

56.594 ± 11.04

55.987 ± 10.32

55.223 ± 10.57

55.137 ± 10.47

Total fat (kg)

NPI

29.542 ± 9.75

26.737 ± 9.38

25.524 ± 8.94

26.213 ± 9.580

 

HPI

35.229 ± 8.25

32.474 ± 7.72

29.598 ± 7.68†‡

29.068 ± 9.18†‡

Visceral fat (kg)

NPI

3.277 ± 1.24

2.839 ± 1.22

2.695 ± 1.07

2.527 ± 1.01†‡

 

HPI

3.295 ± 0.88

2.916 ± 0.79

2.662 ± 0.75

2.445 ± 0.71†‡

Fat percentage (%)

NPI

32.3 ± 7.9

30.5 ± 8.3

29.9 ± 8.2

30.2 ± 8.3

 

HPI

37.4 ± 6.1

35.7 ± 5.9

34.0 ± 6.6

33.4 ± 7.2

Energy Balance (kcal/d)

NPI

+ 92 ± 521

−751 ± 147

−521 ± 304†‡

−413 ± 304

 

HPI

+ 34 ± 348

−635 ± 102

−524 ± 83†‡

−444 ± 71

Physical Activity

NPI

1.22 ± 0.09

1.42 ± 0.07

1.31 ± 1.97†‡

1.30 ± 0.07†‡

 

HPI

1.19 ± 0.12

1.40 ± 0.09

1.33 ± 1.82†‡

1.28 ± 0.04†‡

Metabolic Syndrome parameters:

    

Waist circumference (cm)

NPI

105.1 ± 7.4

102.7 ± 7.9†‡

99.2 ± 6.3†‡

98.9 ± 7.4†‡

 

HPI

101.6 ± 11.8

97.2 ± 9.6†‡

95.1 ± 9.9†‡

93.3 ± 9.1†‡

Blood Pressure (mmHg)

NPI

137/83 ± 11/5

130/80 ± 13/5

129/80 ± 15/6

132/78 ± 16/9

 

HPI

135/86 ± 19/13

128/80 ± 15/16

125/85 ± 16/18

127/82 ± 20/16

Triglycerides (mmol/l)

NPI

1.68 ± 1.15

1.19 ± 0.34

1.17 ± 0.40

1.27 ± 0.61

 

HPI

1.88 ± 0.55

1.37 ± 0.26

1.85 ± 0.21

1.86 ± 1.07

HDL (mmol/l)

NPI

1.44 ± 0.42

1.49 ± 0.31

1.31 ± 0.31

1.58 ± 0.46

 

HPI

1.06 ± 0.33

1.02 ± 0.29

1.13 ± 0.33

1.14 ± 0.25

Glycemia (mmol/l)

NPI

6.15 ± 1.86

6.26 ± 1.76

5.7 ± 1.97

6.28 ± 2.34

 

HPI

5.13 ± 0.68

4.54 ± 0.54

4.98 ± 0.79

4.92 ± 0.50

Other Lipid parameters:

    

Total cholesterol (mmol/l)

NPI

6.08 ± 1.46

5.07 ± 0.95

5.13 ± 1.25

5.56 ± 0.89

 

HPI

5.79 ± 1.07

4.65 ± 1.09

6.18 ± 1.60

6.19 ± 1.08

LDL (mmol/l)

NPI

3.79 ± 1.21

3.05 ±0.87

3.47 ± 1.25

3.43 ± 0.95

 

HPI

3.89 ± 1.01

2.99 ±0.99

4.21 ± 1.34

4.25 ± 0.97

Albumin levels (g/l)

NPI

40.6 ± 3.3

40.3 ± 3.1

34.3 ± 1.8†‡*

35.3 ± 2.2†‡

 

HPI

40.8 ± 2.4

41.3 ± 2.6

41.5 ± 2.6*

41.0 ± 3.2*

Pro-inflammatory factors:

     

CRP (mg/l)

NPI

5.09 ± 4.06

3.64 ± 3.69

4.18 ± 5.60

3.68 ± 4.12

 

HPI

4.19 ± 2.33

3.80 ± 3.48

3.04 ± 3.23

2.99 ± 2.05

orosomucoid (mg/l)

NPI

0.85 ± 0.16

0.80 ± 0.19

0.75 ± 0.19

0.84 ± 0.15

 

HPI

0.91 ± 0.29

0.80 ± 0.33

0.91 ± 0.25

0.84 ± 0.41

Renal function:

     

creatinine levels (mmol/l)

NPI

89.4 ± 19.9

89.1 ± 18.8

80.1 ± 20.7

81.1 ± 20.4

 

HPI

84.9 ± 22.2

88.2 ± 24.1

86.1 ± 23.7

84.0 ± 21.3

Cockroft (ml/min)

NPI

100.3 ± 28.3

95.4 ± 24.2

107.1 ± 27.9

106.6 ± 32.0

 

HPI

111.8 ± 23.7

104.5 ± 24.9

106.7 ± 23.4

109.0 ± 24.4

  1. * : p < 0.05 to compare the percentage change between D0 and D20, D90 and D180 in the two groups (High Protein Intake versus Normal Protein Intake) using the Bonferroni test.
  2. : p < 0.05 to compare the value at the follow-up time with the baseline value (D0) within each group, as calculated by mixed-model repeated-measures analysis of variance.
  3. : p < 0.05 to compare the value at the follow-up time with the end of the residential programme (D20) within each group, as calculated by mixed-model repeated-measures analysis of variance.