Variable | Groups | D0 | D20 | D90 | D180 |
---|---|---|---|---|---|
Body composition measured by DEXA: | |||||
Weight (kg) | NPI | 90.3 ± 11.6 | 86.5 ± 11.0† | 84.4 ± 11.1†‡ | 85.4 ± 12.1†‡ |
HPI | 94.1 ± 15.2 | 90.7 ± 14.5† | 87.1 ± 13.6†‡ | 86.4 ± 15.0†‡ | |
BMI (kg/m2) | NPI | 32.1 ± 4.2 | 30.7 ± 3.8† | 29.9 ± 3.5†‡ | 30.3 ± 3.7†‡ |
HPI | 35.2 ± 4.2 | 33.9 ± 4.1† | 32.6 ± 4.3†‡ | 32.4 ± 4.7†‡ | |
Lean (kg) | NPI | 58.287 ± 7.47 | 57.323 ± 7.56† | 56.488 ± 7.89† | 56.798 ± 7.99† |
HPI | 56.594 ± 11.04 | 55.987 ± 10.32 | 55.223 ± 10.57† | 55.137 ± 10.47† | |
Total fat (kg) | NPI | 29.542 ± 9.75 | 26.737 ± 9.38† | 25.524 ± 8.94† | 26.213 ± 9.580† |
HPI | 35.229 ± 8.25 | 32.474 ± 7.72† | 29.598 ± 7.68†‡ | 29.068 ± 9.18†‡ | |
Visceral fat (kg) | NPI | 3.277 ± 1.24 | 2.839 ± 1.22† | 2.695 ± 1.07† | 2.527 ± 1.01†‡ |
HPI | 3.295 ± 0.88 | 2.916 ± 0.79† | 2.662 ± 0.75† | 2.445 ± 0.71†‡ | |
Fat percentage (%) | NPI | 32.3 ± 7.9 | 30.5 ± 8.3† | 29.9 ± 8.2† | 30.2 ± 8.3† |
HPI | 37.4 ± 6.1 | 35.7 ± 5.9† | 34.0 ± 6.6† | 33.4 ± 7.2† | |
Energy Balance (kcal/d) | NPI | + 92 ± 521 | −751 ± 147† | −521 ± 304†‡ | −413 ± 304‡ |
HPI | + 34 ± 348 | −635 ± 102† | −524 ± 83†‡ | −444 ± 71‡ | |
Physical Activity | NPI | 1.22 ± 0.09 | 1.42 ± 0.07† | 1.31 ± 1.97†‡ | 1.30 ± 0.07†‡ |
HPI | 1.19 ± 0.12 | 1.40 ± 0.09† | 1.33 ± 1.82†‡ | 1.28 ± 0.04†‡ | |
Metabolic Syndrome parameters: | |||||
Waist circumference (cm) | NPI | 105.1 ± 7.4 | 102.7 ± 7.9†‡ | 99.2 ± 6.3†‡ | 98.9 ± 7.4†‡ |
HPI | 101.6 ± 11.8 | 97.2 ± 9.6†‡ | 95.1 ± 9.9†‡ | 93.3 ± 9.1†‡ | |
Blood Pressure (mmHg) | NPI | 137/83 ± 11/5 | 130†/80 ± 13/5 | 129†/80 ± 15/6 | 132/78 ± 16/9 |
HPI | 135/86 ± 19/13 | 128†/80 ± 15/16 | 125†/85 ± 16/18 | 127/82 ± 20/16 | |
Triglycerides (mmol/l) | NPI | 1.68 ± 1.15 | 1.19 ± 0.34 | 1.17 ± 0.40 | 1.27 ± 0.61 |
HPI | 1.88 ± 0.55 | 1.37 ± 0.26 | 1.85 ± 0.21 | 1.86 ± 1.07 | |
HDL (mmol/l) | NPI | 1.44 ± 0.42 | 1.49 ± 0.31 | 1.31 ± 0.31‡ | 1.58 ± 0.46 |
HPI | 1.06 ± 0.33 | 1.02 ± 0.29 | 1.13 ± 0.33 | 1.14 ± 0.25 | |
Glycemia (mmol/l) | NPI | 6.15 ± 1.86 | 6.26 ± 1.76 | 5.7 ± 1.97‡ | 6.28 ± 2.34 |
HPI | 5.13 ± 0.68 | 4.54 ± 0.54† | 4.98 ± 0.79 | 4.92 ± 0.50 | |
Other Lipid parameters: | |||||
Total cholesterol (mmol/l) | NPI | 6.08 ± 1.46 | 5.07 ± 0.95† | 5.13 ± 1.25† | 5.56 ± 0.89 |
HPI | 5.79 ± 1.07 | 4.65 ± 1.09† | 6.18 ± 1.60 | 6.19 ± 1.08 | |
LDL (mmol/l) | NPI | 3.79 ± 1.21 | 3.05 ±0.87† | 3.47 ± 1.25 | 3.43 ± 0.95 |
HPI | 3.89 ± 1.01 | 2.99 ±0.99† | 4.21 ± 1.34 | 4.25 ± 0.97 | |
Albumin levels (g/l) | NPI | 40.6 ± 3.3 | 40.3 ± 3.1 | 34.3 ± 1.8†‡* | 35.3 ± 2.2†‡ |
HPI | 40.8 ± 2.4 | 41.3 ± 2.6 | 41.5 ± 2.6* | 41.0 ± 3.2* | |
Pro-inflammatory factors: | |||||
CRP (mg/l) | NPI | 5.09 ± 4.06 | 3.64 ± 3.69 | 4.18 ± 5.60 | 3.68 ± 4.12 |
HPI | 4.19 ± 2.33 | 3.80 ± 3.48 | 3.04 ± 3.23 | 2.99 ± 2.05 | |
orosomucoid (mg/l) | NPI | 0.85 ± 0.16 | 0.80 ± 0.19 | 0.75 ± 0.19 | 0.84 ± 0.15 |
HPI | 0.91 ± 0.29 | 0.80 ± 0.33 | 0.91 ± 0.25 | 0.84 ± 0.41 | |
Renal function: | |||||
creatinine levels (mmol/l) | NPI | 89.4 ± 19.9 | 89.1 ± 18.8 | 80.1 ± 20.7 | 81.1 ± 20.4 |
HPI | 84.9 ± 22.2 | 88.2 ± 24.1 | 86.1 ± 23.7 | 84.0 ± 21.3 | |
Cockroft (ml/min) | NPI | 100.3 ± 28.3 | 95.4 ± 24.2 | 107.1 ± 27.9 | 106.6 ± 32.0 |
HPI | 111.8 ± 23.7 | 104.5 ± 24.9 | 106.7 ± 23.4 | 109.0 ± 24.4 |