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Table 3 Comparison of fatigue between the two groups within subgroups categorized by baseline vitamin C level.

From: Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial

   Vitamin C Group
(n = 70)
Placebo Group
(n = 71)
p value†
   Baseline 2 hours after intervention 1 day after intervention Baseline 2 hours after intervention 1 day after intervention  
Fatigue right now* Higher 5.74 ± 1.98 5.26 ± 2.23 5.28 ± 2.40 5.47 ± 2.17 5.25 ± 2.30 5.53 ± 2.22 0.206
  Lower 5.54 ± 2.09 4.94 ± 1.85 4.66 ± 2.30 5.60 ± 1.99 5.37 ± 1.68 5.80 ± 2.13 0.004
  1. *Fatigue was measured using a numeric rating scale, 0-10.
  2. Higher and Lower groups were divided by 50th percentile (10.95 μg/ml in trial group, 11.95 μg/ml in placebo group) of baseline plasma vitamin C level.
  3. †p value from ANCOVA with adjustments for the time factor and baseline measurements.