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Table 2 Comparison of fatigue, plasma vitamin C levels, and oxidative stress between the two groups.

From: Intravenous Vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial

 

Vitamin C Group

(n = 70)

Placebo Group

(n = 71)

p value‡

 

Baseline

2 hours after intervention

1 day after intervention

Baseline

2 hours after intervention

1 day after intervention

 

Fatigue right now*

5.64 ± 2.02

5.10 ± 2.04

4.97 ± 2.33

5.54 ± 2.07

5.31 ± 2.00

5.66 ± 2.16

0.004

Usual fatigue during the previous 24 hours

5.59 ± 1.56

-

5.37 ± 2.06

5.77 ± 1.73

-

5.55 ± 1.79

0.870

Worst fatigue during the previous 24 hours

7.16 ± 1.83

-

6.47 ± 2.13

7.14 ± 1.77

-

6.82 ± 1.97

0.202

Plasma vitamin C level (μg/ml)

12.66 ± 6.50

267.90 ± 141.83

-

12.13 ± 4.99

12.52 ± 5.70

-

< 0.001

Oxidative stress (mmol/dl H2O2)†

311.76 ± 74.15

184.46 ± 59.41

296.11 ± 64.37

310.89 ± 74.90

327.21 ± 78.80

303.72 ± 81.26

< 0.001

  1. *Fatigue was measured using a numeric rating scale, 0-10.
  2. †Oxidative stress was measured using the Free Oxygen Radicals Test (FORT).
  3. ‡p value from ANCOVA.