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Table 2 Plasma tocopherols (T) concentrations after supplementation with the α-tocopherol or tocotrienol-rich fraction (TRF) treatments (Mean values ± SEM, n = 10).

From: Alpha-tocotrienol is the most abundant tocotrienol isomer circulated in plasma and lipoproteins after postprandial tocotrienol-rich vitamin E supplementation

 

α-T

 

TRF

 

α-T

γ-T

 

α-T

γ-T

   

μM

  

0 h*

23.38 ± 1.03

0.36 ± 0.12

 

22.95 ± 1.26

0.35 ± 0.15

2 h

26.31 ± 1.81

0.63 ± 0.15

 

22.98 ± 1.20

0.57 ± 0.18

   Change†

2.90 ± 1.63

0.29 ± 0.14

 

0.05 ± 0.65

0.22 ± 0.17

4 h

32.65 ± 2.49‡

1.42 ± 0.12‡

 

26.45 ± 1.89‡

1.70 ± 0.28‡

   Change

9.26 ± 1.00

1.06 ± 0.17

 

3.51 ± 1.23

1.34 ± 0.34

5 h

36.38 ± 3.17‡

1.64 ± 0.15‡

 

28.15 ± 2.61‡

1.96 ± 0.40‡

   Change

12.98 ± 2.79

1.27 ± 0.22

 

5.20 ± 1.93

1.61 ± 0.46

6 h

37.4 ± 3.51‡

1.57 ± 0.17‡

 

30.13 ± 2.91‡

2.15 ± 0.41‡

   Change

14.00 ± 3.25

1.22 ± 0.19

 

7.17 ± 2.18

1.80 ± 0.48

8 h

37.8 ± 3.59‡

1.48 ± 0.27‡

 

29.79 ± 2.30‡

1.76 ± 0.22‡

   Change

14.39 ± 3.32

1.13 ± 0.29

 

6.85 ± 1.39

1.42 ± 0.29

24 h

32.92 ± 3.58

0.35 ± 0.16

 

26.79 ± 1.81

0.20 ± 0.11

   Change

9.52 ± 3.41

-0.02 ± 0.17

 

3.83 ± 1.07

-0.14 ± 0.19

AUC 24 h

353.52 ± 30.40§

9.92 ± 1.68

 

286.16 ± 19.85§

11.10 ± 1.47

  1. T, tocopherols; TRF, tocotrienol-rich fraction; AUC, area under the curve (arbitrary unit); α-T, alpha-tocopherol; γ-T, γ-tocopherol.
  2. * No significant differences in plasma α-T and γ-T concentrations at baseline (0 h) were found between the treatments.
  3. † Changes were calculated as the difference between values at each postprandial interval and baseline (0 h).
  4. ‡ Significant increment from baseline (0 h) value, P < 0.05 (Wilcoxon's signed-ranks test).
  5. § Significant difference of AUC for α-T between the treatments, P < 0.05 (Wilcoxon's signed-ranks test).