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Table 3 Antioxidant enzyme activity and lipid peroxidation before and after intervention

From: Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a randomized, double-blind, placebo-controlled trial

 

Placebo (n = 19)

Low-dose (n = 19)

High-dose (n = 19)

SOD activity (U/ml)

   

 Pre-treatment

12.6±0.97

10.1±0.68

11.9±0.98

 Post-treatment

12.2±0.96

12.1±1.03*

14.2±1.15*

 Change

−0.46±0.57

1.95±0.80

2.24±0.86

GPx activity (nmol/min/ml)

   

 Pre-treatment

41.1±3.71

34.3±1.88

34.9±2.53

 Post-treatment

39.1±3.72

37.4±2.27

43.5±2.53**

 Change

−2.00±2.08

3.05±2.15

8.66±2.63

Catalase (nmol/min/ml)

   

 Pre-treatment

103.2±11.5

94.5±8.56

86.9±11.7

 Post-treatment

99.0±13.2

118.3±11.8

135.5±12.3**

 Change

−4.17±12.4

23.8±12.4

48.5±12.3

8-epi-PGF (pg/mg creatinine)a)

  

 Pre-treatment

1450.3±103.7

1519.0±222.3

1516.3±105.9

 Post-treatment

1641.6±136.5

1323.4±106.6

1383.5±120.2

 Change

191.3±107.7

−195.6±147.6

−132.8±127.9

  1. SOD, superoxide dismutase; GPx, glutathione peroxidase; 8-epi-PGF, 8-epi-prostaglandin F.
  2. a)Tested after logarithmic transformation.
  3. Results are expressed as standard error of the mean (SEM).
  4. Tested by Wilcoxon signed-rank test or analysis of covariance (ANCOVA) using a general linear model (GLM) with adjustments for age, sex, BMI, smoking, drinking, systolic BP, diastolic BP, and baseline values.
  5. * P <0.05,** P <0.01 compared with the baseline in each group; P <0.05, †† P <0.01 compared with the placebo group.