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Table 3 Nutritional status and quality of life in lung cancer

From: Role of nutritional status in predicting quality of life outcomes in cancer – a systematic review of the epidemiological literature

First Author, Year, Study Place

Data Collection Period

Study Design

Sample Size

Nutritional Assessment

Quality of Life Assessment

Groups being compared

Key results

Conclusion

Scott HR, 2003, UK [28]

NA

Prospective

106 inoperable NSCLC (stage III and IV)

By stage –

Stage III: n = 78

Stage IV: n = 28

Weight loss*

* defined as loss of more than 5% pre-illness weight in the previous 6 months

EORTC-QLQ-C30

Weight-stable (< 5% weight loss) (n = 61) & Weight-losing (> 5% weight loss) (n = 45)

(a) Global QoL:

Median (range) = 50 (0–100) & 33.3 (0–66.7) respectively for weight-stable & weight-losing groups, p = 0.027.

(b) Symptom scores: Fatigue (P < 0.05) and pain (P < 0.01) were significantly greater in the weight-losing group.

i. Fatigue: –

Median (range) = 55.6 (0–100) & 66.7 (0–100) respectively for weight-stable & weight-losing groups, p = 0.044.

ii. Pain: –

Median (range) = 16.7 (0–100) & 41.7 (0–100) respectively for weight-stable & weight-losing groups, p = 0.007.

Weight loss has an impact on different aspects of quality of life.