Table 6 Serum calcium and urinary calcium:creatinine following single-dose vitamin D3 (70,000 IU) in pregnant participants
From: Pharmacokinetics of a single oral dose of vitamin D3 (70,000 IU) in pregnant and non-pregnant women
Total serum calcium conc. (mmol/L) | Albumin-adjusted serum calcium concentration (mmol/L) | Urine calcium:creatinine ratio (mmol/mmol) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Follow-up time | Na | Mean (SD) | Mean (SD) | Range | # > 2.60 | Na | Meanb | Median (IQR) | Range | # > 1.0 |
0 days | 27 | 2.29 (0.08) | 2.40 (0.05) | 2.25 to 2.5 | 0 | 27 | 0.14 | 0.20 (0.32) | 0.01 to 0.69 | 0 |
2 days | 13 | 2.31 (0.09) | 2.43 (0.07) | 2.27 to 2.51 | 0 | – | – | – | – | – |
4 days | 13 | 2.30 (0.08) | 2.43 (0.06) | 2.32 to 2.56 | 0 | – | – | – | – | – |
2nd to 4th week (days 7 to 27) | 27 | 2.30 (0.10) | 2.43 (0.09) c | 2.24 to 2.57 | 0 | 33 | 0.33 d | 0.31 (0.31) | 0.06 to 1.05 | 3 |
5th to 8th week (days 28 to 55) | 20 | 2.29 (0.07) | 2.43 (0.05) | 2.34 to 2.51 | 0 | 35 | 0.31d | 0.41 (0.31) | 0.05 to 1.48 | 4 |
9th to 11th week (days 56 to 76) | 14 | 2.39 (0.11) | 2.46 (0.06) | 2.37 to 2.61 | 1 | 28 | 0.33 d | 0.36 (0.36) | 0 to 1.74 | 2 |
Total | 114 | 2.31 (0.09) | 2.42 (0.07) | 2.24 to 2.61 | 1 | 123 | 0.24 | 0.33 (0.36) | 0 to 1.74 | 9 |
N | Mean (SD) | Mean (SD) | Range | # > 3.00 | ||||||
Cord Blood | 12 | 2.57 (0.23) | 2.68 (0.16) | 2.28 to 2.9 | 0 | – | – | – | – | – |