Skip to main content

Table 2 Summary of the secondary outcomes implemented in ARCLI across all time points

From: A randomized controlled trial investigating the effect of Pycnogenol and BacopaCDRI08 herbal medicines on cognitive, cardiovascular, and biochemical functioning in cognitively healthy elderly people: the Australian Research Council Longevity Intervention (ARCLI) study protocol (ANZCTR12611000487910)

  Training Baseline 3 month 6 month 12 month
Screening Medical history & screen (GDS, MMSE, DRS-II)
Demographic Q
Medical screen (ie BMI, MMSE, medication use) Medical screen (ie BMI, MMSE, medication use) Medical screen (ie BMI, MMSE, medication use) Medical screen (ie BMI, MMSE, medication use)
Biochemical Fasting Glucose & Insulin*
APOE & SNP
F2 Isoprostanes
Cytokines* & CRP
MBA
Telomere length
F2 isoprostanes
Cytokines* & CRP
MBA
- F2 isoprostanes
Cytokines* & CRP
MBA
Telomere length
Cardiovascular - Brachial BP
Aortic BP
carotid-femoral PWV
Brachial BP
Aortic BP
carotid-femoral PWV
Brachial BP
Aortic BP
carotid-femoral PWV
Brachial BP
Aortic BP
carotid-femoral PWV
Health FFQ
Chalder Fatigue
Leeds Sleep evaluation Trait anxiety
General Health Q
State anxiety
Leeds Sleep Evaluation
BDI-II
POMS
General Health Q
State anxiety
Leeds Sleep Evaluation
BDI-II
General Health Q
State anxiety
Leeds Sleep Evaluation
BDI-II
FFQ
General Health Q
State anxiety
Leeds Sleep Evaluation
BDI-II
Other NEO PI-R
WASI
    Estimate of compliance
  1. * = Analysis performed for morning participants only
  2. GDS = Geriatric Depression Scale, MMSE = Mini Mental State Examination, DRS = Mattis Dementia Rating Scale, Q = Questionnaire, APOE = Apolipoprotein E, SNP = Single Nucleotide Polymorphisms, WASI = Wechsler Abbreviated Scale of Intelligence FFQ = Food Frequency Questionnaire, NEO PI-R = NEO Personality-Inventory Revised, POMS = Profile of Mood States, BMI = Body Mass Index, CRP = C Reactive Protein, MBA = Multiple Blood Analysis, BP = Blood Pressure, PWV = Pulse Wave Velocity