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Table 3 Demographic distribution of cases and controls according to their genotypes and homocysteine, vitamin B12 and folic acid levels

From: Association of Methylentetraydrofolate Reductase (MTHFR) 677 C > T gene polymorphism and homocysteine levels in psoriasis vulgaris patients from Malaysia: a case-control study

 

Cases

(CC)

(n = 19)

Cases

(CT or TT)

(n = 22)

Controls

(CC)

(n = 21)

Controls

(CT or TT)

(n = 22)

*P-value

Males, n (%)

11 (42.10)

11 (50.00)

10 (47.60)

11 (50.00)

 

Chinese

3 (27.27)

3 (27.27)

2 (20.00)

2 (18.18)

 

Indian

2 (18.18)

2 (18.18)

2 (20.00)

4 (36.36)

 

Malay

6 (54.55)

6 (54.55)

6 (60.00)

5 (45.45)

 

Females, n (%)

8 (42.10)

11 (50.00)

11 (52.38)

11 (50.00)

 

Chinese

2 (25.00)

3 (27.27)

3 (27.27)

4 (36.36)

 

Indian

3 (37.50)

5 (45.45)

5 (45.45)

4 (36.36)

 

Malay

3 (37.50)

3 (27.27)

3 (27.27)

3 (27.27)

 

Age, mean ± SD

38.41 ± 12.36

45.91 ± 13.17

43.43 ± 11.93

43.64 ± 10.84

 

PASI score,

mean ± SD

9.22 ± 10.85

6.37 ± 4.97

N/A

N/A

 

Homocysteine (μmol/L)

14.92 ± 4.13

16.31 ± 4.56

15.42 ± 3.81

14.39 ± 3.59

[p = 0.440]

Vitamin B12 (pg/mL)

482.22 ± 156.98

465.84 ± 210.73

396.38 ± 96.06

444.20 ± 112.19

[p = 0.270]

Folic acid (ng/mL)

7.66 ± 3.91

7.24 ± 4.61

6.62 ± 3.19

9.14 ± 6.40

[p = 0.270]

  1. * P-values obtained for the F-test for the homocysteine, vitamin B12 and folic acid levels in cases and controls with different genotypes.