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Table 7 Multi regression analysis in which MTHFR polymorphism, Homocysteine level, HCV genotype and lipid profile as a independent variables for steatosis

From: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil

Variables OR (CI 95%) p* OR adjusted p OR adjusted p
Gender: F/M 1.1 (0.6-2.0) 0.88 1.1(0.5-2.3) 0.90 1.1 (0.5-2.3) 0.87
HOMA ≥ 2.5 1.5 (0.7-3.2) 0.35 1.3 (0.6-2.9) 0.40 1.4 (0.7-3.1) 0.35
LDL cholesterol ≥ 130 0.5 (0.2-1.6) 0.35 0.6 (0.2-1.9) 0.35 - (**) -
HDL cholesterol ≤ 40 1.1 (0.5-2.4) 0.84 0.9 (0.4-2.1) 0.82 1.0 (0.4-2.2) 0.93
Total Cholesterol ≥ 200 0.8 (0.2-2.9) 0.75 - (**) - 0.9 (0.2-3.6) 0.96
Triglyceride ≥ 150 0.6 (0.2-1.8) 0.38 0.6 (0.2-1.9) 0.40 0.6 (0.2-1.9) 0.37
TT+CT (MTHFR) 0.8 (0.4-1.5) 0.64 1.0 (0.5-2.1) 0.94 1.0 (0.5-2.1) 0.95
Homocysteine ≥ 9 1.6 (0.8-3.3) 0.18 1.6 (0.7-3.3) 0.24 1.6 (0.7-3.3) 0.25
  1. *Fisher Test ** Collinearity
  2. References values:
  3. Triglyceride < 150 mg/dL, Total Cholesterol < 200 mg/dL, LDL-c < 130 mg/dL, HDL-c > 40 mg/dL, HOMA: < 2.5, Homocysteine < 9.0 μmol/L
  4. CI: confidence interval