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Table 4 Genotype frequencies of the 677C/T (MTHFR) polymorphisms in CHC patients according genotype and histopathological classification

From: Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil

  Genotype frequencies (%)
MTHFR TT CT CC p
Steatosis (n = 104) 5.7 40.4 53.8 0.80
No Steatosis (n = 70) 7.1 41.4 51.4  
Fibrosis 1+2 (n = 116) 5.1 37.9 56.9 0.21
Fibrosis 3+4 (n = 58) 8.6 46.5 44.8  
Genotype 1 (n = 113) 4.4 35.4 60.1 0.01*
Genotype Non-1 (n = 61) 9.8 50.8 39.3  
  1. *p significative