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Table 2 Effect of vitamin A supplementation on biochemical parameters in WNIN/Ob lean and obese rats

From: Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats

 

AI

AII

BI

BII

Plasma corticosterone (ng/mL)

227 ± 50

170 ± 15

256 ± 27

287 ± 34

Plasma retinol (μg/dL)

28 ± 0.5

28 ± 0.5

40 ± 0.6

43 ± 2.0

Liver total retinol (mg/g tissue)

0.9 ± 0.1

9.8 ± 0.4##

0.4 ± 0.02

8.1 ± 0.3##

Visceral fat retinol (μg/g tissue)

4.0 ± 1.2

41 ± 2.7##

2.0 ± 0.1

4.8 ± 2.0##

  1. Values are means ± S.E of 8 rats. Mean values with## mark are significant at P < 0.001 level (by one-way ANOVA). Comparisons were made between normal and high vitamin A-fed groups of each phenotype (AI-Lean: 2.6 mg vitamin A/kg diet, AII-Lean: 129 mg vitamin A/kg diet, BI-Obese: 2.6 mg vitamin A/kg diet and BII-Obese: 129 mg vitamin A/kg diet)