Table 2 Biochemical and haematological measurements at baseline and at 6 months of supplementation by intervention group
Multiple Micronutrient Supplementation group (n = 104) | Comparative 'standard of care' multivitamins group (n = 110) | |||
|---|---|---|---|---|
Measurement | Median (IQR) | P-value | Median (IQR) | p-value |
Vitamin B12 (pmol/L) | ||||
Baseline | 285.5 (216.5 - 371.8) | <0.001 | 280.0 (211.5 - 386.3) | 0.78 |
6 months | 401.5 (264.3 - 518.8) | 288.5 (198.8 - 391.0) | ||
Change | 90.5 (-0.8 - 203.5) | 10.0 (-73.8 - 83.8) | ||
Folate (nmol/L) | ||||
Baseline | 17.3 (13.5 - 26.6) | <0.001 | 15.7 (11.9 - 22.1) | 0.44 |
6 months | 27.7 (21.1 - 33.4) | 16.5 (11.7 - 22.1) | ||
Change | 8.0 (-0.3 - 17.1) | -0.6 (-3.5 - 5.8) | ||
Haemoglobin (g/dl) | ||||
Baseline | 10.0 (8.7 - 11.2) | 0.04 | 9.8 (8.8 - 11.2) | <0.001 |
6 months | 10.9 (9.4 - 11.7) | 10.6 (9.6 - 11.7) | ||
Change | 0.3 (-0.4 - 0.9) | 0.6 (-0.2 - 1.4) | ||
CD4+ count (cells/μL) | ||||
Baseline | 1201 (822 - 1556) | 0.16 | 1033 (728 - 1406) | 0.52 |
6 months | 1039 (725 - 1358) | 1043 (704 - 1484) | ||
Change | -137 (-348 - 254) | 35 (-278 - 352) | ||