Table 4 Expression of essential DNA repair genes in seven randomly selected subjects during kiwifruit consumption and after wash-out
Before | After | Diff | Change | p | ||||
|---|---|---|---|---|---|---|---|---|
Mean | SEM | Mean | SEM | Mean | SEM | (%) | ||
Cyclin-dependent kinase inhibitor 1A (p21) | 5.32 | 0.1 | 5.28 | 0.2 | -0.04 | 0.2 | -0.8 | 0.80 |
Replication protein A1 (RPA1) | 6.15 | 0.1 | 6.31 | 0.1 | 0.16 | 0.2 | 2.6 | 0.28 |
Xeroderma pigmentosum, complementation group A (XPA) | 5.56 | 0.2 | 5.38 | 0.2 | -0.18 | 0.2 | -3.2 | 0.30 |
Excision reapir cross-complementing protein 1 (ERCC1) | 3.55 | 0.1 | 3.48 | 0.2 | -0.07 | 0.2 | -2.0 | 0.67 |
Excision reapir cross-complementing protein 2 (ERCC2) | 4.87 | 0.1 | 4.79 | 0.3 | -0.08 | 0.3 | -1.6 | 0.77 |
8-oxoguanine DNA glycosylas (OGG1) | 4.83 | 0.1 | 4.83 | 0.1 | 0 | 0.2 | 0.0 | 1.00 |
Proliferating cell nuclear antigen (PCNA) | 5.06 | 0.2 | 5.01 | 0.2 | -0.05 | 0.2 | -1.0 | 0.75 |
X-ray repair cross-complementing protein (XRCC1) | 4.07 | 0.2 | 3.92 | 0.1 | -0.15 | 0.2 | -3.7 | 0.41 |
NAD(P)H dehydrogenase, quinone 1 (NQO1) | 7.40 | 0.1 | 7.32 | 0.2 | -0.08 | 0.2 | -1.1 | 0.54 |
Nuclease (multifunctional DNA repair enzyme) 1 (APEX1) | 3.08 | 0.1 | 3.00 | 0.2 | -0.08 | 0.2 | -2.6 | 0.52 |
Homolog recombination protein (RecA homolog, E. coli)(RAD51) | 11.68 | 0.3 | 11.58 | 0.2 | -0.1 | 0.3 | -0.9 | 0.81 |
Xeroderma pigmentosum, complementation group C (XPC) | 4.49 | 0.1 | 4.59 | 0.2 | 0.1 | 0.2 | 2.2 | 0.58 |