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Table 3 Endogenous DNA damage and DNA repair activity in lymphocytes, before and after kiwifruit intervention; Arbitrary units (n = 24)

From: Supplementation of a western diet with golden kiwifruits (Actinidia chinensis var.'Hort 16A':) effects on biomarkers of oxidation damage and antioxidant protection

Fruits

Before

After

Diff

Differ (%)

p

  

Mean

SEM

Mean

SEM

Mean

SEM

  

FPG-sensitive sites

1

196.38

73.7

130.33

85.3

-66.05

112.7

-34

0.01

 

2

188.58

61.5

148.26

106.7

-40.32

123.2

-21

0.12

Endonuclease III-sensitive sites1

1

139.42

71.1

104.00

59.8

-35.42

92.9

-25

0.20

 

2

138.17

41.2

92.25

62.1

-45.92

74.5

-33

0.04

Resistance towards H2O2 oxidation

1

283.08

43.9

189.25

117.2

-93.83

125.2

-33

0.00

 

2

278.00

51.6

191.52

124.5

-86.48

134.8

-31

0.00

Base exision repair (BER)

1

48.43

16.3

46.61

14.5

-1.82

21.8

-4

0.69

 

2

52.54

13.8

49.11

15.1

-3.43

20.5

-7

0.43

Nucleotide excision repair (NER)2

1

39.38

21.3

38.13

23.9

-1.25

32.0

-3

0.85

 

2

37.71

18.8

35.50

23.3

-2.21

29.9

-6

0.72

  1. SEM: standard error of the mean. 1Based on samples exclusively from the second intervention period (n = 12). 2n = 23.