Criteria | Description |
---|---|
TEMPORALITY | An exposure must be measured prior the disease, for it to be clear which variable might be the cause and which variable might be the result. |
STRENGTH | This criterion requires that the putative cause of an illness be of sufficient strength of association to cause disease. |
BIOLOGICAL GRADIENT | This criterion requires that when the dose of an exposure is increased, the risk of the outcome should also increase |
PLAUSIBILITY | This criterion requires that a theory fit with current biological knowledge. |
CONSISTENCY | This criterion requires consistent evidence from a variety of study designs to support a causal relationship |
EXPERIMENT | This criterion requires that actual experiments be conducted to determine whether the frequency of a disease is altered by an exposure. |