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Table 1 Changes in vital signs following ingestion of caffeinated or decaffeinated espresso coffee1

From: Acute effects of coffee on QT interval in healthy subjects

 

Coffee

P-value2

 

Caffeinated

Decaffeinated

Time

Time × Treatment

 

N = 40

N = 40

  

Systolic blood pressure (mmHg)

    

   basal

107 ± 2

107 ± 2

  

   30 min

112 ± 2a

106 ± 2

<0.05

<0.001

   60 min

111 ± 2a

107 ± 2

  

P-value3

<0.001

0.50

  

Diastolic blood pressure (mmHg)

    

   basal

68 ± 1

67 ± 1

  

   30 min

72 ± 1a

66 ± 1

<0.001

<0.005

   60 min

71 ± 1b

68 ± 1

  

P-value3

<0.001

0.16

  

Heart rate (beats/min)

    

   basal

67 ± 1

66 ± 1

  

   30 min

69 ± 1c

67 ± 1

<0.001

0.16

   60 min

64 ± 1d

65 ± 1e

  

P-value3

<0.001

0.09

  
  1. 1 All values are mean ± SEM. 2 3 × 2 ANOVA for repeated measures.
  2. 3 - P-value compares within group values between basal, 30 min, and 60 min for each variable within each group.
  3. Paired t-test: a P < 0.001 vs. both decaffeinated coffee and basal value. b P < 0.001 vs. basal value and P < 0.05 vs. decaffeinated coffee. c P < 0.05 vs. basal value. d P < 0.005 vs. basal value and P < 0.001 vs 30 min value; e P < 0.05 vs 30 min value.