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Table 2 Fasting concentrations and net incremental areas under the curve after 240 min (net iAUC 0-240 min)1 for inflammatory markers, insulin and triglycerides in 11 (8 women and 3 men) obese non-diabetic subjects in response to the four test-meals

From: Differential effects of dietary protein sources on postprandial low-grade inflammation after a single high fat meal in obese non-diabetic subjects

  Cod Whey Gluten Casein
MCP-1     
   Fasting 22 ± 11 21 ± 7 23 ± 12 21 ± 11
   iAUC 0-240 min (pg/ml·240 min) - 826 ± 1255x - 77 ± 1092y -943 ± 925x -469 ± 757xy
CCL5     
   Fasting 340 ± 238 490 ± 396 490 ± 321 409 ± 297
   iAUC 0-240 min (pg/ml·240 min) 50 764 ± 58 218x - 18 510 ± 81 999y 11 235 ± 55 558yz 44 488 ± 37 862xz
IL-1ra     
   Fasting 68 ± 18 79 ± 39 76 ± 34 66 ± 24
   iAUC 0-240 min (pg/ml·240 min) 743 ± 2 871 -1 972 ± 4 005 -1 454 ± 5 068 2 173 ± 4 320
PDGF-bb1     
   Fasting 40 ± 41 161 ± 260 65 ± 78 110 ± 232
   iAUC 0-240 min (pg/ml·240 min) 11 837 (6 285 - 20 952) 4 303 (2 102 - 6 995) 6 660 (4851 - 10 742) 8 604 (6348 - 10 435)
IFN-g     
   Fasting 25 ± 12 28 ± 25 30 ± 21 28 ± 24
   iAUC 0-240 min (pg/ml·240 min) 865 ± 1 610 -1 300 ± 3 747 -791 ± 2 622 397 ± 2 614
Adiponectin     
   Fasting 1.5 ± 0.5 1.5 ± 0.6 1.5 ± 0.6 1.5 ± 0.5
   iAUC 0-240 min (μg/ml·240 min) -7.7 ± 48 -8.5 ± 49 6.3 ± 38 -6.9 ± 36
Eotaxin     
   Fasting 52 ± 12 53 ± 14 51 ± 14 49 ± 16
   iAUC 0-240 min (pg/ml·240 min) - 45 ± 819 601 ± 2237 - 64 ± 686 983 ± 1039
G-CSF     
   Fasting 11 ± 3 12 ± 6 11 ± 4 12 ± 7
   iAUC 0-240 min (pg/ml·240 min) 23 ± 719 -420 ± 1 242 -114 ± 685 -194 ± 955
IP-10     
   Fasting 579 ± 166 558 ± 109 588 ± 226 542 ± 142
   iAUC 0-240 min (pg/ml·240 min) -2 343 ± 24 198 -10 371 ± 19 737 -3 403 ± 21 448 -5 159 ± 10 121
MIP-1b     
   Fasting 45 ± 16 46 ± 16 44 ± 14 43 ± 15
   iAUC 0-240 min (pg/ml·240 min) -908 ± 1 248 -331 ± 1 411 -302 ± 534 -219 ± 428
VEGF     
   Fasting 7 ± 3 10 ± 6 7 ± 3 8 ± 4
   iAUC 0-240 min (pg/ml·240 min) 693 ± 921 270 ± 1 058 233 ± 448 317 ± 419
Insulin     
   Fasting 65 ± 28 63 ± 33 66 ± 31 62 ± 32
   iAUC 0-240 min (pmol/l·240 min) 41 158 ± 11 003x 73 693 ± 28 022y 38 738 ± 10 691x 50 978 ± 21 477x
Triglycerides     
   Fasting 2.0 ± 1.0 1.8 ± 0.8 1.9 ± 0.7 1.8 ± 0.9
   iAUC 0-240 min (mmol/l·240 min) 138 ± 108 122 ± 95 132 ± 95 127 ± 94
  1. 1All values are means ± SDs (normal distributions; mixed-effects model, Tukey's post hoc correction) or medians with interquartile ranges in parentheses (skewed distribution; mixed-effects model on normal distributed log-transformed data, Tukey's post hoc correction). Meals: energy-free soup plus 100 g butter and 45 g carbohydrate consumed with either 45 g cod, 45 g whey isolate, 45 g gluten or 45 g casein. MCP-1: monocyte chemotactic protein-1; CCL5: Chemokine ligand 5; IL-1ra: interleukin 1 receptor-antagonist; PDGF-bb1: platelet derived growth factor BB; IFN-g: interferon-gamma; G-CSF: granulocyte colony-stimulating factor; IP-10: interferon-gamma induced protein 10 kDa; MIP-1b: macrophage inflammatory protein 1b; VEGF: vascular endothelial growth factor. Values in a row with different superscript letters are significantly different, P < 0.05.
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Nutrition Journal

ISSN: 1475-2891

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