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Table 2 Adjusted prevalence (with standard error) of and adjusted odds ratios (with 95% confidence intervals) for taking folic acid supplements among adults aged ≥ 18 years, by sex and by depression and anxiety status, BRFSS, 2006

From: Use of folic acid and vitamin supplementation among adults with depression and anxiety: a cross-sectional, population-based survey

  Adjusted prevalence* Adjusted odds ratio*
  Taking supplements No supplements Taking supplements
(times/day) < 1 1 to 4   < 1 1 to 4
  % (SE) % (SE) % (SE) AOR 95% CI AOR 95% CI
Men (n = 18, 092)        
   Ever diagnosed depression        
Yes (n = 2, 140) 7.6 (1.1) 45.1 (1.8)¶ 47.3 (1.9)¶ 1.42 1.00-2.00 1.44 1.21-1.71
No (n = 15, 952) 6.4 (0.4) 38.0 (0.6) 55.6 (0.6) 1.00   1.00  
   Ever diagnosed anxiety        
Yes (n = 1, 508) 9.6 (1.8)† 43.6 (2.2)‡ 46.8 (2.3)¶ 1.83 1.18-2.84 1.39 1.13-1.70
No (n = 16, 584) 6.3 (0.4) 38.3 (0.6) 55.4 (0.6) 1.00   1.00  
   EDS        
Yes (n = 1, 162) 10.6 (2.7) 37.5 (2.4) 52.0 (3.1) 1.79 0.96-3.34 1.02 0.80-1.30
No (n = 16, 930) 6.3 (0.4) 38.8 (0.6) 54.9 (0.6) 1.00   1.00  
Women (n = 28, 027)        
   Ever diagnosed depression        
Yes (n = 5, 879) 6.6 (0.6) 52.7 (1.1)‡ 40.7 (1.0)‡ 0.97 0.76-1.24 1.13 1.02-1.26
No (n = 22, 148) 7.2 (0.3) 49.8 (0.5) 43.0 (0.5) 1.00   1.00  
   Ever diagnosed anxiety        
Yes (n = 4, 038) 7.0 (0.8) 51.8 (1.3) 41.3 (1.2) 1.02 0.78-1.33 1.08 0.96-1.22
No (n = 23, 989) 7.1 (0.3) 50.1 (0.5) 42.8 (0.5) 1.00   1.00  
   EDS        
Yes (n = 2, 816) 7.5 (1.2) 49.2 (1.6) 43.2 (1.5) 1.05 0.73-1.51 0.96 0.83-1.10
No (n = 25, 211) 7.0 (0.3) 50.5 (0.5) 42.5 (0.5) 1.00   1.00  
  1. *Adjusted for age, race/ethnicity, education, body mass index, marital status, smoking, leisure-time exercise, and alcohol consumption. †P = 0.065, ‡P < 0.05, and ¶P < 0.001 for comparisons between adults with ever diagnosed depression or anxiety and those without. AOR = Adjusted odds ratio, BRFSS = Behavioral Risk Factor Surveillance System, CI = Confidence interval, EDS = Elevated depressive symptoms, SE = Standard error
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