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Diurnal variation of phenylalanine and tyrosine concentrations in adult patients with phenylketonuria: subcutaneous microdialysis is no adequate tool for the determination of amino acid concentrations

  • Sarah C Grünert1,
  • Corinna M Brichta1, 2,
  • Andreas Krebs1,
  • Hans-Willi Clement2,
  • Reinhold Rauh2,
  • Christian Fleischhaker2,
  • Klaus Hennighausen2,
  • Jörn Oliver Sass1, 3 and
  • K Otfried Schwab1Email author
Contributed equally
Nutrition Journal201312:60

DOI: 10.1186/1475-2891-12-60

Received: 12 February 2013

Accepted: 7 May 2013

Published: 14 May 2013

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
12 Feb 2013 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
2 Mar 2013 Reviewed Reviewer Report - Denise Ney
23 Mar 2013 Reviewed Reviewer Report - Anita MacDonald
27 Mar 2013 Reviewed Reviewer Report - Roman Kandar
12 Apr 2013 Author responded Author comments - Sarah Grünert
Resubmission - Version 3
12 Apr 2013 Submitted Manuscript version 3
1 May 2013 Reviewed Reviewer Report - Anita MacDonald
Resubmission - Version 4
Submitted Manuscript version 4
Publishing
7 May 2013 Editorially accepted
14 May 2013 Article published 10.1186/1475-2891-12-60

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Center for Pediatrics and Adolescent Medicine, University Hospital Freiburg
(2)
Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital Freiburg
(3)
Clinical Chemistry and Biochemistry, University Children’s Hospital Zürich

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